Results 81 to 90 of about 6,533,042 (299)

The patient patient: The importance of knowing your navigator [PDF]

, 2015
In Ontario, Diagnostic Assessment Programs (DAPs) have been implemented to improve the quality of care patients receive during the diagnostic phase of the cancer journey.
Kaan, Melissa, MBA, Holloway, Claire MB, MD PhD FRCSC, Gilbert, Julie E, PhD, Klonikowski, Eric, Wheeler, Sarah M, PhD   +4 more
core   +1 more source

A Non-Invasive Multichannel Hybrid Fiber-Optic Sensor System for Vital Sign Monitoring

Sensors, 2017
In this article, we briefly describe the design, construction, and functional verification of a hybrid multichannel fiber-optic sensor system for basic vital sign monitoring.
Marcel Fajkus, Jan Nedoma, Radek Martinek, Vladimir Vasinek, Homer Nazeran, Petr Siska   +5 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Modelling of vital-sign data from post-operative patients: Machine learning approach to patient monitoring [PDF]

, 2016
Thousands of in-hospital deaths each year in the UK are potentially preventable, being often preceded by physiological deterioration. The current standard of clinical practice for patient monitoring on general wards is the periodic observation of vital ...
Pimentel, Marco A. F.
core   +1 more source

Safer and more efficient vital signs monitoring protocols to identify the deteriorating patients in the general hospital ward: an observational study

Health and Social Care Delivery Research
Background The frequency at which patients should have their vital signs (e.g. blood pressure, pulse, oxygen saturation) measured on hospital wards is currently unknown. Current National Health Service monitoring protocols are based on expert opinion but
Jim Briggs, Ina Kostakis, Paul Meredith, Chiara Dall’ora, Julie Darbyshire, Stephen Gerry, Peter Griffiths, Jo Hope, Jeremy Jones, Caroline Kovacs, Rob Lawrence, David Prytherch, Peter Watkinson, Oliver Redfern   +13 more
doaj   +1 more source

A Device for Automatically Measuring and Supervising the Critical Care Patient’S Urine Output

Sensors, 2010
Critical care units are equipped with commercial monitoring devices capable of sensing patients’ physiological parameters and supervising the achievement of the established therapeutic goals.
Roemi Fernández, Francisco Palacios, Teodor Akinfiev, Abraham Otero   +3 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Defining Patient Experience [PDF]

, 2014
In recent years, perceptions of performance and quality of healthcare organizations have begun to move beyond examining the provision of excellent clinical care, alone, and to consider and embrace the patient experience as an important indicator.
LaVela, Sherri L., PhD, MPH, MBA, Marshburn, Dianne, PhD, RN, NE-BC, Niederhauser, Victoria, DrPH, RN, Wolf, Jason A, PhD, CPXP   +3 more
core   +1 more source