Results 161 to 170 of about 465,365 (351)

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Axillary Artery Aneurysm as an Unforeseen Complication of the Park Bench Position: A Case Report

Bali Journal of Anesthesiology
Proper patient positioning is critical in neurosurgery to optimize surgical access and minimize complications. The park bench (PB) position is frequently employed for posterior fossa procedures due to its neurosurgical advantages but carries risks of ...
Ikhwan Nasir Bin Idris
doaj   +1 more source

Role of Cardiovascular Imaging in Cancer Patients Receiving Cardiotoxic Therapies: A Position Statement on Behalf of the Heart Failure Association (HFA), the European Association of Cardiovascular Imaging (EACVI) and the Cardio-Oncology Council of the European Society of Cardiology (ESC) [PDF]

, 2020
Jelena Čelutkienė, Radek Pudil, Teresa López‐Fernández, Julia Grapsa, Petros Nihoyannopoulos, Jutta Bergler‐Klein, Alain Cohen‐Solal, Dimitrios Farmakis, Carlo G. Tocchetti, Stephan von Haehling, Vassilis I. Barberis, Frank A. Flachskampf, Indrė Čeponienė, Eva Haegler‐Laube, Thomas Suter, Tomas Lapinskas, Sanjay Prasad, Rudolf A. de Boer, Kshama Wechalekar, Markus S. Anker, Zaza Iakobishvili, Chiara Bucciarelli‐Ducci, Jeanette Schulz‐Menger, Bernard Cosyns, Oliver Gaemperli, Yu. N. Belenkov, Jean‐Sébastien Hulot, Maurizio Galderisi, Patrizio Lancellotti, Jeroen J. Bax, Thomas H. Marwick, Ovidiu Chioncel, Tiny Jaarsma, Wilfried Müllens, Massimo Piepoli, Thomas Thum, Stéphane Heymans, Christian Mueller, Brenda Moura, Frank Ruschitzka, José Luis Zamorano, Giuseppe Rosano, Andrew J.S. Coats, Riccardo Asteggiano, Petar Seferović, Thor Edvardsen, Alexander R Lyon   +46 more
openalex   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Changes in the Position of Epidural Catheters Associated with Patient Movement  [PDF]

, 1997
Catherine L. Hamilton, Edward T. Riley, Sheila E. Cohen   +2 more
openalex   +1 more source

The physiological effect of prone positioning and lateral decubitus in non-intubated patients with severe COVID-19: a prospective cohort study

, 2023
Siswanto Siswanto, Oktaviarum Slamet Utama, Guritno Adistyawan, Purwadi Sujalmo, Gusti Putri Devany Tunggadewi, Primavera Nabila Shafa, Taufiq Rohman, Denny Agustiningsih   +7 more
openalex   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Targeting the Tumor: Assessing the Impact of Bladder Volume and Position on Accuracy of Radiation Delivery for Patients with Bladder Cancer [PDF]

, 2017
Andrew Kochan, Ryan Rivest, Katie Galloway, Pascal Lambert, Aldrich Ong, Rashmi Koul, Shahida Ahmed, Bashir Bashir, Harvey Quon   +8 more
openalex   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

Patient Positioning [PDF]

AORN Journal, 2004
openaire   +3 more sources