Results 231 to 240 of about 3,740,894 (266)

Assessing patient preferences for medical decision making - a comparison of different methods. [PDF]

Front Digit Health
Fusiak J, Wolkenstein A, Hoffmann VS.
europepmc   +1 more source

Mr BMT Achieves Systemic Macrophage Replacement With Preservation of Tissue Homeostasis

Advanced Science, EarlyView.
Microglia replacement by bone marrow transplantation (Mr BMT) enables systemic replacement of tissue‐resident macrophages. Despite persistent macrophage and tissue remodeling across multiple organs, core biological functions and innate immune responses remain preserved, supporting long‐term maintenance of organismal homeostasis and the therapeutic ...
Yufei Xu, Miaozhan Zou, Yunshang Bai, Yang He, Zhihao Jin, Baozhi Yang, Jinjin Du, Pei Ouyang, Yuanyuan Cai, Yuheng Zhang, Bingying Du, Chengcheng Ge, Jian‐an Gong, Xiaoyu Li, Yuanyi Zheng, Jing Ding, Bo Peng, Yanxia Rao   +17 more
wiley   +1 more source

Patient Preferences for Low Back Pain Treatments in Iran: A Discrete Choice Experiment. [PDF]

Patient Prefer Adherence
Soofi M, Karamimatin B, Alipoor Z, Kazemi-Karyani A.   +3 more
europepmc   +1 more source

Mitochondria and Neuromast Tagging With Fluorescent Gallium‐Triapine Analogues: In Cellulo MP FLIM and Zebrafish Live Imaging

Advanced Science, EarlyView.
Fluorescent BODIPY‐conjugated thiosemicarbazone ligands and their Ga(III), In(III), and Fe(III) complexes, inspired by Triapine, are developed as theranostic agents. Multiphoton FLIM and confocal microscopy in cancer cells and zebrafish reveal real‐time uptake, mitochondrial localisation, and whilst spectroscopic assays indicated preserved complex ...
Megan J. Green, Michael W. Jones, Merissa Saleem, Haobo Ge, Melita Tvardauskaite, Julia Dudzic, Fernando Cortezon‐Tamarit, Rory L. Arrowsmith, Charareh Pourzand, Gabriele Kociock‐Kohn, Nicholas H. Rees, Jonathan R. Dilworth, Stephen Faulkner, Stanley W. Botchway, David Gurevich, Sofia I. Pascu   +15 more
wiley   +1 more source

Patient Preferences for In-Person vs Remote Care for Long-Term Conditions.

JAMA Netw Open
Lenfant T, Perrodeau E, Ravaud P, Tran VT.   +3 more
europepmc   +1 more source

Patient Preferences Regarding Menopausal Symptoms and Treatments: A Systematic Review of Quantitative Stated-Preference Studies. [PDF]

Patient
Raskin L, Boretti E, Douxfils J, Beaudart C.   +3 more
europepmc   +1 more source

Engineering Immunoregenerative Therapy via an Immunomodulatory Binary Pharmacology Hydrogel Depot for Prolonged Allograft Survival

Advanced Science, EarlyView.
An immunomodulatory hydrogel (iGEL) forms spontaneously upon subcutaneous injection, acting as a tissue‐adhesive depot. It releases anti‐rejection and regenerative agents in response to inflammation, suppressing T‐cell activity, promoting vascular repair, and restoring allograft function without systemic immunosuppression.
Ning Wang, Ruiqi Sun, Yang Fu, Zhonghan Wu, Xinyu Tong, Hong Tang, Wentao Zhao, Zhi Liang, Jintao Zheng, Yanan Guan, Ke Zhou, Penghong Song, Shusen Zheng, Hangxiang Wang, Haiyang Xie   +14 more
wiley   +1 more source

Patient preferences for pancreatic cancer treatment (PERSEUS): a multicenter discrete choice experiment. [PDF]

Health Qual Life Outcomes
Lansbergen MF, Smith IP, van Alphen EN, Augustinus S, Fransen IJM, Wilmink JW, Besselink MG, Molenaar IQ, Homs MYV, de Hingh IHJT, Bonsing BA, Vos-Geelen J, Haberkorn BCM, Vissers PAJ, Nieuwkerk PT, Bijlsma MF, Frederix GWJ, van Laarhoven HWM, Dutch Pancreatic Cancer Group.   +18 more
europepmc   +1 more source

Disrupted TFEB/GDNF–cAMP/ATP Coupling Underlies Astrocytic Dysfunction and Depression in LRRK2 G2019S Parkinson's Mice

Advanced Science, EarlyView.
ABSTRACT The LRRK2 G2019S mutation, a Parkinson's disease–linked variant, has been associated with depression‐like phenotypes, but mechanisms remain unclear. We chart age‐dependent behavioral changes and astrocyte reactivity in G2019S mice and define a pathway connecting LRRK2 to TFEB/GDNF signaling, cellular energetics, and inflammation.
Longping Yao, Maryam Hatami, Sumeyye Koc, Qing Jiang, Thomas Skutella, Yuanfeng Zhang   +5 more
wiley   +1 more source

Patient Preferences for Long-Term Prophylactic Treatment in Hereditary Angioedema: A Discrete-Choice Experiment. [PDF]

Patient
Villa KF, Mansfield C, Yarlas A, Ruggles JA, Bordone L, Kent C, Vass CM.   +6 more
europepmc   +1 more source