Results 171 to 180 of about 18,470 (294)
Long‐Acting Therapeutics in Pediatric Health: Bridging Innovation and Access
Children have distinct therapeutic needs arising from age‐dependent physiology, disease epidemiology, formulation requirements, dosing considerations, and safety vulnerabilities. Despite substantial reductions in childhood mortality over the past three decades, nearly 5 million children under five died in 2023, with infectious diseases continuing to ...
Prajith Venkatasubramanian +5 more
wiley +1 more source
The Governance Gap: Democratizing Drug Development Through Decision Architecture
Drug development is most exposed to governance failure where it can least afford it, in global health. The field has more predictive power than at any point in its history and roughly the same failure rate it had a decade ago. We argue that this paradox persists because the field has invested heavily in prediction science while neglecting decision ...
Craig R. Rayner +16 more
wiley +1 more source
ABSTRACT Open burning plastics is a major environmental health hazard in low‐ and middle‐income countries, releasing toxic pollutants and exacerbating climate change. Although Indonesia prohibits plastic burning, enforcement in rural settings remains fragile.
Sujarwoto Sujarwoto +3 more
wiley +1 more source
Early Impact of the Patient Protection and Affordable Care Act on Delivery of Children's Surgical Care. [PDF]
Routh JC +7 more
europepmc +1 more source
Abstract Sodium‐glucose co‐transporters (SGLTs) mediate sodium and glucose transport across cell membranes. SGLT2 inhibitors have a recognized place within heart failure (HF) guidelines. We evaluated the effect of sotagliflozin on HF and cardiovascular outcomes in participants with type 2 diabetes. Scopus, Medline, Embase and Central were searched from
Maria Anna Bantounou +7 more
wiley +1 more source
Honesty in Difficult Conversations: Insights From Healthcare Professionals
ABSTRACT When being honest is expected to cause emotional distress to those it concerns, it can be difficult to practice. This study examines how honesty is understood and accounted for in situations of emotional, moral and relational complexity. Drawing on semi‐structured interviews with 16 Danish healthcare professionals (8 doctors and 8 nurses), we ...
Anna Louise Z. Malfilâtre +4 more
wiley +1 more source

