Results 121 to 130 of about 700,979 (308)

Patterns of Postictal Abnormalities in Relation to Status Epilepticus in Adults

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Abnormalities on peri‐ictal diffusion‐weighted magnetic resonance imaging (DWI‐PMAs) are well‐established for patients with status epilepticus (SE), but knowledge on patterns of DWI‐PMAs and their prognostic impact is sparse. Methods This systematic review and individual participant data meta‐analysis included observational studies ...
Andrea Enerstad Bolle, Silvana Sarria‐Estrada, Thomas Bonduelle, Bertram Daniel Dynesen, Manuel Toledo, Zhu Chung Che, Kjell Heuser, Anastasios Chatzikonstantinou, Jérôme Aupy, Udaya Seneviratne, Estevo Santamarina Perez, Christoph Patrick Beier   +11 more
wiley   +1 more source

Regional disparities of antidementia drug treatment in Germany: what can we learn for the new generation of Alzheimer’s therapies

Alzheimer’s Research & Therapy
Background Current antidementia drugs can temporarily slow cognitive decline in Alzheimer’s disease but are underused. Regional and socioeconomic disparities, including limited specialist access in rural or deprived areas, may exacerbate inequities and ...
Moritz Platen, Eva Gläser, Volker Dahling, Daniela Gesell, Michael Hauptmann, Dirk Horenkamp-Sonntag, Daniela Koller, Denise Kubat, Ursula Marschall, Cordula Riederer, Hannah Scheibner, Jennifer Schroth, Enno Swart, Bernhard Michalowsky   +13 more
doaj   +1 more source

The Clinical Utility of a Precision Medicine Blood Test Incorporating Age, Sex, and Gene Expression for Evaluating Women with Stable Symptoms Suggestive of Obstructive Coronary Artery Disease: Analysis from the PRESET Registry. [PDF]

, 2019
Background: Evaluating women with symptoms suggestive of coronary artery disease (CAD) remains challenging. A blood-based precision medicine test yielding an age/sex/gene expression score (ASGES) has shown clinical validity in the diagnosis of ...
Budoff, Matthew J, Gul, Burcu, Herman, Lee, Huang, Lin, Kuo, Jane Z, Ladapo, Joseph A, Lansky, Alexandra, Maniet, Bruce, Monane, Mark, Sharp, David   +9 more
core   +1 more source

Predicting Loss of Ambulation in Limb Girdle Muscular Dystrophy R9

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Limb girdle muscular dystrophy type R9 (LGMDR9) results from biallelic variants in FKRP. There is limited data to predict loss of ambulation (LOA) among those with LGMDR9. Methods Participants in an ongoing dystroglycanopathy natural history study (NCT00313677) with FKRP variants who had achieved ambulation and were more than 3 ...
Chandra L. Miller, Lauren N. Coffey, Shelley R. H. Mockler, Katie M. Laubscher, Carrie M. Stephan, M. Bridget Zimmerman, Katherine D. Mathews   +6 more
wiley   +1 more source

Designing a core data set for benign hysterectomy registration system and its implementation in a referral teaching hospital in Northwest Iran

BMC Pregnancy and Childbirth
Background and aims Although minimally invasive hysterectomy offers advantages, abdominal hysterectomy remains the predominant surgical method. Creating a standardized dataset and establishing a hysterectomy registry system present opportunities for ...
Fatemeh Moghadami Asl, Elham Maserat, Maryam Vaezi, Zeinab Mohammadzadeh   +3 more
doaj   +1 more source

Whole‐Body Pattern of Muscle Degeneration and Progression in Sarcoglycanopathies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize whole‐body intramuscular fat distribution pattern in patients with sarcoglycanopathies and explore correlations with disease severity, duration and age at onset. Methods Retrospective, cross‐sectional, multicentric study enrolling patients with variants in one of the four sarcoglycan genes who underwent whole‐body ...
Laura Costa‐Comellas, Mauro Monforte, Angel Sanchez‐Montañez, Penélope Romero‐Duque, Elena Pegoraro, Jordi Díaz‐Manera, Dmitry Vlodavets, Lorenzo Maggi, Marco Moscatelli, Adele D‘Amico, Montse Olivé, Jorge Alonso‐Pérez, Giacomo Comi, José Miguel Escudero‐Fernández, Gabriela S. Urcuyo, Anna Pichiecchio, Angela Berardinelli, Kristl G. Claeys, Claudio Bruno, Chiara Panicucci, Sara Bortolani, Eleonora Torchia, Enzo Ricci, Soledad Monges, Jorge A. Bevilacqua, Jorge Diaz‐Jara, Maggie C. Walter, Simone Thiele, Nicoline Løkken, John Vissing, Susana Quijano‐Roy, Robert Y. Carlier, Nicol C. Voermans, Chiara Marini‐Bettolo, Michela Guglieri, Volker Straub, Lea Leonardis, Francina Munell, David Gómez‐Andrés, Giorgio Tasca   +39 more
wiley   +1 more source

Development of a Prediction Model for Progression Risk in High‐Grade Gliomas Based on Habitat Radiomics and Pathomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate the value of constructing models based on habitat radiomics and pathomics for predicting the risk of progression in high‐grade gliomas. Methods This study conducted a retrospective analysis of preoperative magnetic resonance (MR) images and pathological sections from 72 patients diagnosed with high‐grade gliomas (52 ...
Yuchen Zhu, Yuxi Gong, Weilin Xu, Xingjian Sun, Gefei Jiang, Lei Qiu, Kexin Shi, Mengxing Wu, Yinjiao Fei, Jinling Yuan, Jinyan Luo, Yurong Li, Yuandong Cao, Minhong Pan, Shu Zhou   +14 more
wiley   +1 more source

From data to impact: The societal contributions of neurological and neurosurgical national registries

Societal Impacts
The creation of the electronic medical record (EMR) was one of the greatest advancements in medical documentation. It improved the efficiency and practicality of multi-patient research, such as retrospective case series and cohort studies.
Tiffany Eatz, Chase DeLong, Ashley R. Metzler, Neil Patel, Ian A. Ramsay, Sai Sanikommu, Soumya Shrigiri, Ahmed Abdelsalam, Luis Guada, Michael A. Silva, Dileep R. Yavagal, Sebastian Koch, Robert M. Starke   +12 more
doaj   +1 more source

Strengthening Primary and Chronic Care: State Innovations to Transform and Link Small Practices [PDF]

, 2010
Presents case studies of state policies for reorganizing and improving primary and chronic care delivery among small practices, including leadership and convening, payment incentives, infrastructure support, feedback and monitoring, and ...
Anne K. Gauthier, Kristin Sims-Kastelein, Mary Takach, Neva Kaye   +3 more
core  

Supporting Interoperable Eu Patient Registries: Survey of Registry Holders' Needs [PDF]

Value in Health, 2014
Pristas, I., Doupi, P., Meglic, M., Karanikas, H., Zaletel, M., Brkic, M., Plese, B., Zuriaga, Llorens O.   +7 more
openaire   +2 more sources