Results 71 to 80 of about 1,333,332 (355)

Intron‐oriented HTLV‐1 integration in an adult T‐cell leukemia/lymphoma cell line sustains expression of intact ift81 mRNA

FEBS Letters, EarlyView.
In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi, Yuka Hirosawa, Yusaku Sagisaka, Minami Hama, Satoshi Takeda, Jun A. Komano   +5 more
wiley   +1 more source

Functional Assessment of Chronic Illness Therapy-Fatigue is a reliable and valid measure in patients with active ankylosing spondylitis

Journal of Patient-Reported Outcomes, 2022
Plain English summary Ankylosing spondylitis (AS) is a disease that causes pain and stiffness in the spine. AS is a chronic disease. Most people with AS experience fatigue (a feeling of being very tired or exhausted).
David Cella, William R. Lenderking, Peter Chongpinitchai, Andrew G. Bushmakin, Oluwaseyi Dina, Lisy Wang, Joseph C. Cappelleri, Victoria Navarro-Compán   +7 more
doaj   +1 more source

Patient-reported outcome measures in cardiovascular disease [PDF]

European Heart Journal - Quality of Care and Clinical Outcomes, 2021
AbstractIn today's medical ecosystem, it is vital to measure the outcomes that are most important to the patients. As such, patient-reported outcome measures (PROMS) can be an essential metric to deliver high-quality cardiovascular care, particularly in the subset of patients who remain disappointed with their outcomes.PROMS should be a reproducible ...
openaire   +3 more sources

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source

Goodbye flat lymphoma biology

FEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria, Cèlia Dobaño‐López, Patricia Pérez‐Galán, Christine Bezombes   +3 more
wiley   +1 more source

Systematic review of the psychometric properties of patient-reported outcome measures for foot and ankle in rheumatoid arthritis [PDF]

, 2019
Background Foot problems and pain are common in patients with rheumatoid arthritis. Patient-reported outcome measures provide a standardized method of capturing patients’ perspectives of their functional status and wellbeing.
Cervera Garvi, Pablo, Gijón-Noguerón, Gabriel, Nester, Christopher J., Ortega-Avila, Ana Belen, Ramos Petersen, Laura   +4 more
core  

Trigeminal neurosensory deficit and patient reported outcome measures: the effect on quality of life [PDF]

, 2013
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Cheung, LK, Leung, MYY, McGrath, CPJ
core   +2 more sources

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

Patient empowerment: The need to consider it as a measurable patient-reported outcome for chronic conditions

BMC Health Services Research, 2012
Background Health policy in the UK and elsewhere is prioritising patient empowerment and patient evaluations of healthcare. Patient reported outcome measures now take centre-stage in implementing strategies to increase patient empowerment.
McAllister Marion, Dunn Graham, Payne Katherine, Davies Linda, Todd Chris   +4 more
doaj   +1 more source

Developing a Standard Set of Patient-Centred Outcomes for Inflammatory Bowel Disease—an International, Cross-disciplinary Consensus [PDF]

, 2017
Success in delivering value-based healthcare involves measuring outcomes that matter most to patients. Our aim was to develop a minimum Standard Set of patient-centred outcome measures for inflammatory bowel disease (IBD), for use in different healthcare
Banerjee, Rupa, Bemelman, Willem, Bodger, Keith, Derieppe, Marc, Dignass, Axel, Driscoll, Richard, Feagan, Brian G, Fitzpatrick, Ray, Gaarentstroom-Lunt, Janette, Higgins, Peter D, Kim, Andrew H, Kotze, Paulo Gustavo, Meissner, Jillian, O'Connor, Marian, Ran, Zhi-Hua, Roberts, Charlotte, Sands, Bruce E, Siegel, Corey A, Terry, Helen, Travis, Simon Pl, van Deen, Welmoed K, van der Woude, C Janneke, Vermeire, Séverine, Weaver, Alandra, Yang, Suk-Kyun   +24 more
core   +1 more source