Results 1 to 10 of about 7,176,843 (353)

Development of a novel patient-reported outcome measure to assess signs and symptoms of COVID-19

Journal of Patient-Reported Outcomes, 2022
Background Given the urgent need for vaccines and treatments for coronavirus disease 2019 (COVID-19), the Symptoms of Infection with Coronavirus-19 (SIC), a comprehensive, patient-reported outcome (PRO) measure of signs and symptoms associated with COVID-
Carla Romano, Sheri Fehnel, Jeffrey Stoddard, Jerald Sadoff, Sandy Lewis, Pauline McNulty, Eric K. H. Chan, Emily Evans, Carol Jamieson, Ashley F. Slagle, Allen Mangel, Kelly McQuarrie   +11 more
doaj   +1 more source

Correlated physical and mental health composite scores for the RAND-36 and RAND-12 health surveys: can we keep them simple?

Health and Quality of Life Outcomes, 2022
Background The RAND-36 and RAND-12 (equivalent to versions 1 of the SF-36 Health Survey and SF-12 Health Survey, respectively) are widely used measures of health-related quality of life.
John Roger Andersen, Kyrre Breivik, Inger Elise Engelund, Marjolein M. Iversen, Jorunn Kirkeleit, Tone Merete Norekvål, Kjersti Oterhals, Anette Storesund   +7 more
doaj   +1 more source

Patient-Reported Outcomes

JACC: Heart Failure, 2019
Authors of systematic reviews that include patient-reported outcomes (PROs) should have a good understanding of how patient-reported outcome measures (PROMs) are developed, including the constructs they are intended to measure, their reliability, validity and responsiveness.
Johnston, Bradley C., Patrick, Donald L., Devji, Tahira, Maxwell, Lara J., Bingham, Clifton O., Beaton, Dorcas E., Boers, Maarten, Briel, Matthias, Busse, Jason W., Carrasco-Labra, Alonso, Christensen, Robin, Da Costa, Bruno R., Dib, Regina El, Lyddiatt, Anne, Ostelo, Raymond W., Shea, Beverley, Singh, Jasvinder, Terwee, Caroline B., Williamson, Paula R., Gagnier, Joel J., Tugwell, Peter, Guyatt, Gordon H.   +21 more
  +11 more sources

Electronic patient-reported monitoring of symptoms during follow-up of ovarian cancer patients: a feasibility study

BMC Cancer, 2022
Background Ovarian cancer patients require monitoring for relapse. Innovative follow-up methods are increasingly being explored. An electronic patient-reported outcome (ePRO) follow-up pathway was developed for women treated for ovarian cancer.
Fiona Kennedy, Leanne Shearsmith, Marie Holmes, Zoe Rogers, Rob Carter, Uschi Hofmann, Galina Velikova   +6 more
doaj   +1 more source

Symptom burden and health-related quality of life impacts of smoldering multiple myeloma: the patient perspective

Journal of Patient-Reported Outcomes, 2020
Background Smoldering multiple myeloma (SMM) is an early form of multiple myeloma (MM). SMM is typically considered asymptomatic, and research on how it affects health-related quality of life (HRQoL) is limited. This study assessed the symptoms and HRQoL
Milenka Jean-Baptiste, Katharine S. Gries, William R. Lenderking, John Fastenau   +3 more
doaj   +1 more source

Outcome selection for tissue-agnostic drug trials for immune-mediated inflammatory diseases: a systematic review of core outcome sets and regulatory guidance

Trials, 2022
Background Tissue-agnostic drug development provides a paradigm shift in precision medicine and requires innovative trial designs. However, outcome selection for such trials can prove challenging.
Olalekan Lee Aiyegbusi, Lavinia Ferrante di Ruffano, Ameeta Retzer, Philip N. Newsome, Christopher D. Buckley, Melanie J. Calvert   +5 more
doaj   +1 more source

Patient and clinician opinions of patient reported outcome measures (PROMs) in the management of patients with rare diseases: a qualitative study

Health and Quality of Life Outcomes, 2020
Background Rare diseases may be life-threatening or chronically debilitating conditions. Patient care needs are often complex and challenging to coordinate and deliver effectively.
Olalekan Lee Aiyegbusi, Fatima Isa, Derek Kyte, Tanya Pankhurst, Larissa Kerecuk, James Ferguson, Graham Lipkin, Melanie Calvert   +7 more
doaj   +1 more source

Key considerations to reduce or address respondent burden in patient-reported outcome (PRO) data collection

Nature Communications, 2022
The collection of patient-reported outcomes (PROs) may capture patients’ assessments of their health status. Here authors highlight PRO-specific issues that should be considered to minimise respondent burden in clinical trials and routine care.
Olalekan Lee Aiyegbusi, Jessica Roydhouse, Samantha Cruz Rivera, Paul Kamudoni, Peter Schache, Roger Wilson, Richard Stephens, Melanie Calvert   +7 more
doaj   +1 more source

‘Give Us The Tools!’: development of knowledge transfer tools to support the involvement of patient partners in the development of clinical trial protocols with patient-reported outcomes (PROs), in accordance with SPIRIT-PRO Extension

BMJ Open, 2021
Objectives (a) To adapt the Standard Protocol Items: Recommendations for Interventional Trials (SPIRIT)-patient-reported outcome (PRO) Extension guidance to a user-friendly format for patient partners and (b) to codesign a web-based tool to support the ...
Ameeta Retzer, Anita Slade, Melanie Calvert, Rebecca Mercieca-Bebber, Gary Price, Lesley Roberts, Claudia Rutherford, Olalekan Lee Aiyegbusi, Samantha Cruz Rivera, Richard Stephens, Rav Verdi, Roger Wilson, Philip Edge, Lesley Gosden   +13 more
doaj   +1 more source

Co-production of a feasibility trial of pacing interventions for Long COVID

Research Involvement and Engagement, 2023
Plain English summary The World Health Organisation defines Long COVID as a condition which impacts people 3 months after they first had COVID-19. Some of the symptoms that characterise Long COVID symptoms include fatigue, breathlessness and brain fog ...
Grace M. Turner, Christel McMullan, Olalekan Lee Aiyegbusi, Sarah E. Hughes, Anita Walker, Felicity Jeyes, Yvonne Adler, Amy Chong, Lewis Buckland, David Stanton, Elin Haf Davies, Shamil Haroon, Melanie Calvert   +12 more
doaj   +1 more source