Results 271 to 280 of about 7,176,843 (353)

Global trends in patient-reported outcomes and quality-of-life research for breast cancer: a 20-year bibliometric study. [PDF]

Cancer Causes Control
Li M, Li X, Shang J.
europepmc   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Patient-reported outcomes and measures for vaginal relaxation syndrome management: a systematic review. [PDF]

Health Qual Life Outcomes
Chen H, Meng J, Li Q, Luo X, Wang Y, Chen Y, Niu X, Wei D.   +7 more
europepmc   +1 more source

Active use of patient-reported outcomes during chemo-or immunotherapy for bladder cancer-preliminary data from a national randomized trial

, 2020
Gry Assam Taarnhøj, Christoffer Johansen, Henriette Lindberg, Andreas Carus, Rikke Hedegaard Dahlrot, Helle Pappot   +5 more
openalex   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Comparison of long-term patient reported outcomes of excisional and incisional corporoplasties for Peyronie's disease. [PDF]

Basic Clin Androl
Preece PD, Sahdev V, Davis PG, Rees RW.
europepmc   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Correction to "Patient-Reported Outcomes Among an Observational Cohort of Individuals With Chronic Low Back Pain". [PDF]

JOR Spine
europepmc   +1 more source

Patient-reported outcomes after ipsilateral radiation therapy for N2b tonsillar squamous cell carcinoma. [PDF]

Discov Oncol
Abana CO, Garden AS, Brandon Gunn G, Chronowski GM, Mohamed ASR, Frankart AJ, Geier N, Bahig H, Barbon CEA, Hutcheson K, Takiar V, Fuller CD, Frank SJ, Rosenthal DI, Phan J.   +14 more
europepmc   +1 more source