Fecal Microbiota Transplantation Modulates Th17/Treg Balance via JAK/STAT Pathway in ARDS Rats
Fecal microbiota transplantation (FMT) alleviates lung and intestinal injury in lipopolysaccharide (LPS)‐induced acute respiratory distress syndrome (ARDS) in rats. This study demonstrates that FMT restores the balance between Th17 and Treg cells, inhibits the JAK/STAT pathway, and modulates cytokine levels, reducing inflammation and lung damage. These
Dongwei Zhang+8 more
wiley +1 more source
Innovative learning from simulated patient complaints [PDF]
Repeated inquiries have highlighted issues with patient safety, communication and the exploration of complaints, emphasising the interplay between each in securing the optimum patients’ journey through health and social care provision (Francis 2013 ...
Brown, Jo, Collins, Guy
core +1 more source
Patient Safety Events Related to the Placement of Drug-Eluting Stents
Patient Safety Authority
doaj +1 more source
Gastrointestinal tolerability of meloxicam compared to diclofenac in osteoarthritis patients. International MELISSA Study Group. Meloxicam Large-scale International Study Safety Assessment [published erratum appears in Br J Rheumatol 1998 Oct;37(10):1142] [PDF]
C J Hawkey+10 more
openalex +1 more source
A detailed workflow for recombinant GALC production and characterization is presented to support enzyme replacement therapy for Krabbe disease. In vitro assays demonstrate that physiological GALC doses restore enzymatic activity and autophagic flux without affecting cell viability, whereas higher doses impair autophagy and reduce viability.
Ambra Del Grosso+5 more
wiley +1 more source
SOME FUNDAMENTALS OF MEDICAL ELECTRONICS V: RECORDING AND DISPLAY SYSTEMS, PATIENT SAFETY
Dennis W. Hill
openalex +1 more source
Pharmacokinetics and safety of glimepiride at clinically effective doses in diabetic patients with renal impairment [PDF]
Bernd Rosenkranz+5 more
openalex +1 more source
The novelty of this study showed that the injection of exosomes produced from ADMSCs in combination with Roflumilast poses a more favorable therapeutic outcome for CKD induced by Adriamycin, compared to therapy with exosomes or Roflumilast alone. Roflumilast and exosomes treatment lowered the expression of the apoptotic, fibrotic, and inflammatory ...
Mohamed Ali+5 more
wiley +1 more source
Understanding Healthcare Disparities in Pennsylvania: We Need Your Help
Patient Safety Authority
doaj +1 more source
Safety of Oral Vancomycin in Functionally Anephric Patients
Charles S Bryan, Wain L. White
openalex +1 more source