Results 191 to 200 of about 2,281,903 (348)

The public's perceptions of patient safety in healthcare. [PDF]

open access: yesIsr J Health Policy Res
Kagan I   +4 more
europepmc   +1 more source

Matrix Tropism Influences Endometriotic Cell Attachment Patterns

open access: yesAdvanced Functional Materials, EarlyView.
The influence of substrate stiffness and multicellular coculture on endometriotic cell attachment to extracellular matrix‐laden microarrayed islands is reported. This model investigates early endometriotic cell attachment, aiming to capture “lesion initiation events”.
Hannah S. Theriault   +7 more
wiley   +1 more source

Machine Learning‐Enabled Polymer Discovery for Enhanced Pulmonary siRNA Delivery

open access: yesAdvanced Functional Materials, EarlyView.
This study provides an efficient approach to train a machine learning model by merging heterogeneous literature data to predict suitable polymers for siRNA delivery. Without the need for extensive laboratory synthesis, the machine learning enabled a virtual screening and successfully predicted a polymer that is validated for effective gene silencing in
Felix Sieber‐Schäfer   +10 more
wiley   +1 more source

Adalimumab‐Poloxamer Conjugate for Bio‐Better: Enhanced Stability and Function

open access: yesAdvanced Functional Materials, EarlyView.
Antibody‐polymer conjugates, particularly poloxamer conjugates, enhance antibody stability by improving tolerance to physicochemical stress and attenuating proteolysis by proteases. Furthermore, the higher affinity observed with poloxamer conjugation compared to standard PEGylation results in improved therapeutic efficacy in rheumatoid arthritis mouse ...
Jaewon Roh   +3 more
wiley   +1 more source

Transducer Materials Mediated Deep Brain Stimulation in Neurological Disorders

open access: yesAdvanced Functional Materials, EarlyView.
This review discusses advanced transducer materials for improving deep brain stimulation (DBS) in neurological disorders. These materials respond to light, ultrasound, or magnetic fields, enabling precise, less invasive neuromodulation. Their stimulus‐responsive properties enhance neural control and adaptive therapy, paving the way for next‐generation ...
Di Zhao   +5 more
wiley   +1 more source

Anionic Citrate‐Based 3D‐Printed Scaffolds for Tunable and Sustained Orthobiologic Delivery to Enhance Tissue Regeneration

open access: yesAdvanced Functional Materials, EarlyView.
A potent anionic citric acid‐based 3D‐printed scaffold is developed for the sustained and controlled release of orthobiologics to enhance orthopedic therapeutic efficacy. Comprehensive in vivo studies demonstrated effective bone fusion and high safety at a low dose of BMP‐2 delivered by the system, establishing it as a promising platform for safe ...
Se‐Hwan Lee   +12 more
wiley   +1 more source

Dual‐Nanoparticle Engineered Hydrogel Reverses Bicellular Oxidative Stress to Accelerate Diabetic Fracture Healing

open access: yesAdvanced Functional Materials, EarlyView.
CD105‐LNPs and PS‐LNPs can deliver α‐lipoic acid to bone marrow mesenchymal stem cells and bone marrow‐derived macrophages, reversing high glucose‐induced oxidative stress while enhancing osteogenesis and M2 polarization. Integrating both nanoparticles into glucose‐responsive hyaluronic acid hydrogel forms DLNPs@HA hydrogel, which accelerates diabetic ...
Yanzhi Zhao   +11 more
wiley   +1 more source

Battery‐Free, Wireless Multi‐Sensing Platform for Comprehensive Management of Pressure Injury and Hygiene

open access: yesAdvanced Functional Materials, EarlyView.
A battery‐free, wireless device for real‐time monitoring of pressure injury and hygiene integrates pressure (≈10 kPa), temperature (≈40 °C), and NH3 gas sensing with antibacterial functionality. Enabled by near‐field communication, it ensures simultaneous, interference‐free mechanical and chemical monitoring, offering a practical solution for pressure ...
Myungwoo Choi   +19 more
wiley   +1 more source

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