Results 261 to 270 of about 16,692,900 (403)

Acetylation of the Mitochondrial Chaperone GRP75 Governs ER‐Mitochondrial Calcium Homeostasis and Hepatocyte Insulin Resistance

Advanced Science, EarlyView.
Overnutrition exacerbates insulin resistance (IR) and is linked to excessive mitochondrial protein acetylation. However, it remains unclear whether and how mitochondrial protein acetylation influences IR. GCN5L1‐dependent downregulation of GRP75 acetylation at K567/612 consequently enhances ER‐mitochondrial calcium flux and induces ER stress.
Danni Wang, Jiaqi Zhang, Xinyu Yang, Qiqi Zhang, Xiuya Hu, Xin Lu, Hanni Li, Xue Bai, Kai Zhang, Michael N. Sack, Yongsheng Chang, Yingmei Wang, Lingdi Wang, Lu Zhu   +13 more
wiley   +1 more source

Enhanced Monofocal IOLs Improve Patient Satisfaction in Phaco-Vitrectomy for ERM. [PDF]

Clin Ophthalmol
Ota J, Matsunaga M, Haga F, Suzumura A, Yamada K, Shimizu H, Kachi S, Ota I, Miyake G, Mokuno K, Inooka D, Iwata E, Akahori T, Nishiguchi KM, Kaneko H.   +14 more
europepmc   +1 more source

Communication Skills Training for Physicians Improves Patient Satisfaction

Journal of general internal medicine, 2016
Adrienne Boissy, A. Windover, D. Bokar, M. Karafa, K. Neuendorf, R. Frankel, J. Merlino, M. Rothberg   +7 more
semanticscholar   +1 more source

Intravenous iRGD‐Guided, RBC‐Membrane Camouflaged Lactococcus Lactis Remodels Cold NSCLC and Enhances PD‐1 Blockade

Advanced Science, EarlyView.
This study presents an engineered probiotic platform, iRGD‐mRBC@FOLactis, combining red blood cell membrane cloaking and tumor‐penetrating peptide iRGD for enhanced PD‐1 blockade. The platform improves tumor targeting, immune cell activation and therapeutic efficacy in lung cancer, demonstrating significant promise in overcoming PD‐1/PD‐L1 therapy ...
Chen Chen, Junmeng Zhu, Xiao Liu, Jie Shao, Aoxing Chen, Yi Mei, Xinyin Zhang, Qinyi Chen, Lin Li, Baorui Liu   +9 more
wiley   +1 more source

Adherence Barriers, Patient Satisfaction, and Depression in Albanian Ambulatory Patients. [PDF]

Healthcare (Basel)
Qirko S, Prifti V, Kicaj E, Cercizaj R, Rogozea L.   +4 more
europepmc   +1 more source

Engineered Mesenchymal Stem Cell–NK Cell Complexes for Spatially Targeted and Functionally Revitalized Cancer Immunotherapy

Advanced Science, EarlyView.
IL‐15‐engineered stem cell–NK cell complexes, assembled via bioorthogonal chemistry, enable effective lung cancer immunotherapy. Abstract Natural killer (NK) cells represent a powerful immunotherapeutic strategy due to their intrinsic cytotoxicity and ability to target tumor cells independently of antigen presentation.
Qian Zhang, Bo Yin, Munaiwaier Sabier, Youlan Yang, Mengling Wu, Zhouping Zhao, Xuanzhi Luo, Yuehong Zhong, Xiuming Zhu, Jie Zhang, Jing Wang, Kai Chen, Fei Ruan, Wei Zhang, Zhimin Lu, Jiong Wang   +15 more
wiley   +1 more source

Patient Satisfaction Following a Session With a Kidney Genetic Counselor. [PDF]

Kidney Int Rep
Hager MM, Stein Q, Hendricks E, Westemeyer M, Conway E, Vance C, Raible D, McQueen K, Pitman T.   +8 more
europepmc   +1 more source

Spatial Transcriptional Dynamics of CD74⁺ B Cells in Tertiary Lymphoid Structures Drive Immune Evolution in Penile Squamous Cell Carcinoma

Advanced Science, EarlyView.
In penile squamous cell carcinoma, a higher tertiary lymphoid structure score is associated with improved survival. This is mediated by CD74⁺ B cells, which exhibit early developmental plasticity and the ability to differentiate into plasma cells. Functioning as a molecular switch, these cells activate naive T cells via HLA‐DRA–CD4 interaction, thereby
Ting Xue, Chuangzhong Deng, Jingya Liu, Ru Yan, Jing Li, Xiheng Hu, Xueying Li, Xiao Xiao, Jietian Jin, Hongzhen Tang, Desi Chen, Zihan Zuo, Yujie Liang, Dongbin Wang, Bonan Chen, Hui Han, Zaishang Li   +16 more
wiley   +1 more source

Appointment Density, Message Responsiveness, and Patient Satisfaction.

JAMA Netw Open
Rotenstein L, Toretsky C, Khoong E, Sarkar U, Adler-Milstein J.   +4 more
europepmc   +1 more source

Assessment of patient satisfaction with the hemodialysis experience using an integrated decision-making approach with rough numbers. [PDF]

Sci Rep
Gao J, Han M, Ban B.
europepmc   +1 more source