Results 91 to 100 of about 6,688,553 (311)
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Automated Quantification of Stroke Damage on Brain Computed Tomography Scans: e-ASPECTS [PDF]
European Medical Journal Neurology, 2015 Emergency radiological diagnosis of acute ischaemic stroke requires the accurate detection and appropriate interpretation of relevant imaging findings.
James Hampton-Till +8 more
doaj
Other title: Title from HTML header (viewed Nov. 9, 2011): Judicial Selection Commission
, 2016 Updated irregularly; Began in 2002?; Title from main search screen (publisher's Web site, viewed Nov. 9, 2011).; At head of title: State of Connecticut.; Harvested from the web on 4/18/16Official website of the Connecticut Judicial Selection Commission ...
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FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Patient experience of care in a student-faculty collaborative practice [PDF]
, 2014 Student Run Clinics (SRCs) are a popular means of caring for the underserved while providing valuable medical education opportunities. Reports of patient experience surveys are rare in this setting.
Laura Huppert +19 more
core +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Journal of Pain Research, 2022 Lisa Goudman,1– 5 Philippe Rigoard,6– 8 Maxime Billot,6 Rui V Duarte,9 Sam Eldabe,10 Maarten Moens1– 4,11 1Department of Neurosurgery, Universitair Ziekenhuis Brussel, Jette, 1090, Belgium; 2STIMULUS Consortium (Research and Teaching Neuromodulation VUB ...
Goudman L +5 more
doaj
The ubiquitin system in normal and infected germinal center B cells
FEBS Letters, EarlyView.The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
Other title: Title from HTML header (viewed Nov. 9, 2011): Judicial Selection Commission
, 2015 Updated irregularly; Began in 2002?; Title from main search screen (publisher's Web site, viewed Nov. 9, 2011).; At head of title: State of Connecticut.; Harvested from the web on 4/18/15Official website of the Connecticut Judicial Selection Commission ...
core