Results 131 to 140 of about 19,068,215 (411)

Tissue Doppler echocardiography and biventricular pacing in heart failure: Patient selection, procedural guidance, follow-up, quantification of success

Cardiovascular Ultrasound, 2004
Asynchronous myocardial contraction in heart failure is associated with poor prognosis. Resynchronization can be achieved by biventricular pacing (BVP), which leads to clinical improvement and reverse remodeling. However, there is a substantial subset of
Baumann Gert, Eddicks Stephan, Walde Torsten, Witte Joachim, Bondke Hans-Jürgen, Reibis Rona Katharina, Knebel Fabian, Borges Adrian   +7 more
doaj   +1 more source

Heart Transplant: Current Indications and Patient Selection [PDF]

, 2018
Heart transplant remains the gold standard treatment for end-stage heart failure, in spite of the recent advances in pharmacological treatment and device therapy. As expected, since the first heart transplant was performed 50 years ago, outcomes in heart
Díez-López, Carles, González-Costello, José, López-Cardoza, Ulises   +2 more
core   +1 more source

Targeting rapid TKI‐induced AXL upregulation overcomes adaptive ERK reactivation and exerts antileukemic effects in FLT3/ITD acute myeloid leukemia

Molecular Oncology, EarlyView.
Adaptive ERK reactivation hinders FLT3 tyrosine kinase inhibitor (TKI) treatment in FLT3/ITD acute myeloid leukemia. Here, we report that FLT3 TKI treatment rapidly induces AXL expression and upregulation that is temporally associated with the adaptive ERK reactivation.
Tessa S. Seale, Li Li, J. Kyle Bruner, Melody Chou, Bao Nguyen, Jaesung Seo, Ruiqi Zhu, Mark J. Levis, Christine A. Pratilas, Donald Small   +9 more
wiley   +1 more source

Desktop software to identify patients eligible for recruitment into a clinical trial: using SARMA to recruit to the ROAD feasibility trial

Journal of Innovation in Health Informatics, 2010
Background Recruitment to trials in primary care is often difficult, particularly when practice staff need to identify study participants with acute conditions during consultations.
Shaun Treweek, Ewan Pearson, Natalie Smith, Ron Neville, Paul Sargeant, Brian Boswell, Frank Sullivan   +6 more
doaj   +1 more source

Combined spatially resolved metabolomics and spatial transcriptomics reveal the mechanism of RACK1‐mediated fatty acid synthesis

Molecular Oncology, EarlyView.
The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu, Jinqiu Li, Junqi Ma, Ayshamgul Hasim   +3 more
wiley   +1 more source

Adverse outcomes in nontrial like patients on commercial HeartMate 3 LVAD support

JHLT Open, 2023
Background: Patient selection for real-world use of HeartMate 3 left ventricular assist device (HM3 LVAD) differs from that of clinical trials. We assessed adverse-event rates between “nontrial like” (NTL) and “trial like” (TL) patients who underwent ...
Laura Coyle, APN, Colleen Gallagher, BSN, Nicole Graney, APN, Lisa Kukla, APN, Robin Paliga, APN, Kylie Hughes, APN, Rachel Pedersen, BA, Kathleen Schultz, APN, Adam JT Schuldt, MD, PhD, Nasir Sulemanjee, MD, Gregory P. Macaluso, MD, Sunil Pauwaa, MD, James Monaco, MD, Mark Dela Cruz, MD, William G. Cotts, MD, Nikhil Narang, MD, Patroklos S. Pappas, MD, Antone J. Tatooles, MD, Vinh Q. Chau, MD   +18 more
doaj  

Demand, Selection and Patient Outcomes in German Acute Care Hospitals [PDF]

In times of peak demand hospitals may fail to deliver the high standard of treatment quality that they are able to offer their patients at regular times.
Axel Focke, Boris Augurzky, Christoph Schwierz, Jürgen Wasem   +3 more
core  

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

Molecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld, Stefan Kühberger, Ricarda Graf, Christine Beichler, Markus Braun, Nadia Dandachi, Ellen Heitzer, Gerald W. Prager   +7 more
wiley   +1 more source

Scar Revision Surgery: The Patient's Perspective

Archives of Plastic Surgery, 2015
Background Insufficient satisfaction outcome literature exists to assist consultations for scar revision surgery; such outcomes should reflect the patient's perspective.
Benjamin H Miranda, Anna Y Allan, Daniel P Butler, Paul D Cussons   +3 more
doaj   +1 more source

Assortment Optimization for Patient-Provider Matching [PDF]

arXiv
Rising provider turnover forces healthcare administrators to frequently rematch patients to available providers, which can be cumbersome and labor-intensive. To reduce the burden of rematching, we study algorithms for matching patients and providers through assortment optimization. We develop a patient-provider matching model in which we simultaneously
arxiv