Results 131 to 140 of about 6,688,553 (311)

Imaging predictors of pleural response in stage IV non–small cell lung cancerCentral MessagePerspective

JTCVS Open
Objective: The relationship between imaging and pathologic findings after systemic therapy in stage IV non–small cell lung cancer with pleural involvement remains unclear. Morphologic and metabolic imaging changes may predict pleural clearance and inform
Nicolas Zhou, DO, MSc, Ioannis Vlahos, MD, Zamaan Hooda, MD, Wayne L. Hofstetter, MD, Reza J. Mehran, MD, Ravi Rajaram, MD, MSc, David C. Rice, MBBch, Boris Sepesi, MD, Stephen G. Swisher, MD, Ara A. Vaporciyan, MD, Garrett L. Walsh, MD, Kyle G. Mitchell, MD, MSc, Mara B. Antonoff, MD   +12 more
doaj   +1 more source

Unveiling Patient Satisfaction: Exploring Demographics, Interactions, and Health-Seeking Behavior [PDF]

Objective: This study examined the social context of the patient visit (demographics, waiting room experience, patient-provider interaction) and their relationship to satisfaction with the quality of care when seeking medical treatment.
Crowther, Vanessa B, Farmer, Errick D, Shaw-Johnson, Cassandra, Mathis, Arlesia L, Green-Weir, Robbya R, Woodley, Pia S, Weatherspoon, Marilyn A   +6 more
core   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Predicting survival of patients treated with antibody–drug conjugates in early-phase clinical trials using AI-quantified 3D body composition on CT scans

Frontiers in Oncology
BackgroundBody composition has a significant impact on the prognosis of cancer patients. However, little is known about its impact on the efficacy and safety of antibody–drug conjugates (ADCs), despite the need for accurate patient profiling to ensure ...
Matthieu Delaye, Littisha Lawrance, Littisha Lawrance, Younes Belkouchi, Younes Belkouchi, Felix Wirth, Pierre Decazes, Alexandre Bône, Kaïssa Ouali, Antoine Hollebecque, Cristina Smolenschi, Rastislav Bahleda, Anas Gazzah, Stéphane Champiat, François-Xavier Danlos, François-Xavier Danlos, Clémence Hénon, Kristi Beshiri, Madona Sakkal, Aurélien Marabelle, Jean-Marie Michot, Vincent Ribrag, Claudia Parisi, Christophe Massard, Vincent Goldschmidt, Pierre Vera, Pierre Vera, Santiago Ponce-Aix, Nathalie Lassau, Nathalie Lassau, Samy Ammari, Samy Ammari, Capucine Baldini, Capucine Baldini   +33 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Taking Time and Making Space for Patient and Caregiver Partners [PDF]

Patient and caregiver engagement is a paramount element to ensure the voice of lived experience is integrated and prioritized in research. However, what it looks like to actually participate in authentic patient and caregiver engagement can be ...
Hives, L., Hamilton, R.
core   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Secukinumab in the treatment of psoriasis: patient selection and perspectives

Psoriasis: Targets and Therapy, 2018
Eric J Yang,1,2 Kristen M Beck,1 Wilson Liao1 1Department of Dermatology, University of California San Francisco, San Francisco, CA, USA; 2Chicago Medical School, Rosalind Franklin University of Medicine and Science, North Chicago, IL, USA Abstract ...
Yang EJ, Beck KM, Liao W
doaj  

Patient Safety Report Program

This archived document is maintained by the Oregon State Library as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Began with 2011; ceased with 2012Includes bibliographical ...

core  

Selection Effects in Regulated Markets [PDF]

This paper analyzes dynamic selection effects that arise in a regulated market where price structures are determined by a regulator or central management. Consumers come in different types where each type requires a different service or treatment.
Maarten C.W. Janssen, Alexei Parakhonyak
core