Results 21 to 30 of about 2,641,102 (341)
The current role of secondary cytoreductive surgery for recurrent ovarian cancer
Ovarian cancer represents worldwide the second most frequent and the most fatal gynecological malignancy, with approximately two thirds of the patients presenting with advanced disease. Cytoreductive surgery, primary or after neoadjuvant chemotherapy, in
Eelco de Bree +2 more
doaj +1 more source
The author joins the discussion on selection of patients in the face of life-saving resources initiated in the Journal by Parsons and Lock, Mooney and the editorial in the December 1980 issue. In this article several selection systems are discussed. The author is in favour of a `criteria-system'. The criteria for such a system are elaborated.
openaire +2 more sources
Evaluating candidate reactions to selection practices using organisational justice theory [PDF]
Objectives: This study aimed to examine candidate reactions to selection practices in postgraduate medical training using organisational justice theory.
Carr, V. +4 more
core +1 more source
Association of radiation dose intensity with overall survival in patients with distant metastases
Background Patients with metastatic cancer referred to radiation oncology have diverse prognoses and there is significant interest in personalizing treatment.
Johnny Kao +9 more
doaj +1 more source
Background Patients with multimorbidity who frequently contact the general practice, use emergency care or have unplanned hospitalisations, may benefit from a proactive integrated care intervention. General practitioners are not always aware of who these
Marianne Heins +3 more
doaj +1 more source
CD47‐SIRPα blocking‐based immunotherapy: Current and prospective therapeutic strategies
Background The CD47‐signal regulatory protein alpha (SIRPα) ‘don't eat me’ signalling axis is perhaps the most prominent innate immune checkpoint to date.
Renée Bouwstra +2 more
doaj +1 more source
Adverse outcomes in nontrial like patients on commercial HeartMate 3 LVAD support
Background: Patient selection for real-world use of HeartMate 3 left ventricular assist device (HM3 LVAD) differs from that of clinical trials. We assessed adverse-event rates between “nontrial like” (NTL) and “trial like” (TL) patients who underwent ...
Laura Coyle, APN +18 more
doaj +1 more source
BackgroundThe role of stereotactic ablative radiation therapy (SABR) as local treatment option after chemotherapy for locally advanced pancreatic cancer (LAPC) is evolving.
D. Doppenberg +24 more
doaj +1 more source
The effect of PD-L1 testing on the cost-effectiveness and economic impact of immune checkpoint inhibitors for the second-line treatment of NSCLC [PDF]
Background: Immune checkpoint inhibitors improve outcomes compared with chemotherapy in lung cancer. Tumor PD-L1 receptor expression is being studied as a predictive biomarker. The objective of this study was to assess the cost-effectiveness and economic
Abdel-Rahman +25 more
core +3 more sources
Patients with advanced hepatocellular carcinoma (HCC) have a very limited survival rate even after the recent inclusion of kinase inhibitors or immune checkpoint inhibitors in the therapeutic armamentarium. A significant problem with the current proposed
Elias Kouroumalis +2 more
doaj +1 more source

