Results 21 to 30 of about 1,444,460 (248)

Is There a Place for Somatostatin Analogues for the Systemic Treatment of Hepatocellular Carcinoma in the Immunotherapy Era?

Livers, 2022
Patients with advanced hepatocellular carcinoma (HCC) have a very limited survival rate even after the recent inclusion of kinase inhibitors or immune checkpoint inhibitors in the therapeutic armamentarium. A significant problem with the current proposed
Elias Kouroumalis, Ioannis Tsomidis, Argryro Voumvouraki   +2 more
doaj   +1 more source

A Tractography-Based Grading Scale of Brain Arteriovenous Malformations Close to the Corticospinal Tract to Predict Motor Outcome After Surgery

Frontiers in Neurology, 2019
Background: Surgical decision-making for brain arteriovenous malformations (AVMs) close to the corticospinal tract (CST) is always challenging. The purpose of this study was to develop a tractography-based grading scale to improve preoperative risk ...
Maogui Li, Maogui Li, Maogui Li, Maogui Li, Pengjun Jiang, Pengjun Jiang, Pengjun Jiang, Pengjun Jiang, Rui Guo, Rui Guo, Rui Guo, Rui Guo, Qingyuan Liu, Qingyuan Liu, Qingyuan Liu, Qingyuan Liu, Shuzhe Yang, Shuzhe Yang, Shuzhe Yang, Shuzhe Yang, Jun Wu, Jun Wu, Jun Wu, Jun Wu, Yong Cao, Yong Cao, Yong Cao, Yong Cao, Shuo Wang, Shuo Wang, Shuo Wang, Shuo Wang   +31 more
doaj   +1 more source

Mapping MAGE-A4 expression in solid cancers for targeted therapies

Frontiers in Oncology
Melanoma-associated antigen A4 (MAGE-A4) is a promising target for anticancer therapy. However, limited contemporary data are available on the details of MAGE-A4 protein expression in different cancer types.
Christin Habigt, Sylvie Rottey, Iben Spanggaard, Juanita S. Lopez, Elena Garralda, Emiliano Calvo, Oliver Bechter, Oliver Bechter, Jayesh Desai, Rachel Galot, Leena Gandhi, Florian Heil, Natascha Rieder, Ivan Dimitrov, Iris Martinez Quetglas, Christian Heichinger, Nino Keshelava, Andreas Roller   +17 more
doaj   +1 more source

Evaluation of triage methods used to select patients with suspected pandemic influenza for hospital admission: cohort study

Health Technology Assessment, 2010
Background: Triage methods are necessary in emergency departments to provide clinicians with a reliable method for determining each patient’s risk of adverse outcome.
S Goodacre, K Challen, R Wilson, M Campbell   +3 more
doaj   +1 more source

Patient Selection for Mitral Transcatheter Edge-to-Edge Repair

Methodist DeBakey Cardiovascular Journal, 2023
Mitral regurgitation (MR) is one of the most common valvular heart diseases, with many patients remaining non-suitable for surgical interventions. Transcatheter edge-to-edge repair (TEER) is a rapidly evolving procedure that allows safe and effective ...
Habib Layoun, Serge C. Harb, Amar Krishnaswamy, Rhonda Miyasaka, James Yun, Samir R. Kapadia   +5 more
doaj   +1 more source

Communication and Language Profiles of Children Treated for Posterior Fossa Brain Tumors

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cognitive and language deficits are frequently reported sequelae of posterior fossa brain tumors (PFBT). Typically, delayed onset impedes prompt assessment and early intervention. This has devastating implications for quality of life.
Zara Sved, Meghan Hesse, Jennie Cusiter, Annabel Webb, Kimberley Docking   +4 more
wiley   +1 more source

The HIT Network for Children and Adolescents With CNS Tumors Facilitates Improvements of Diagnostic Assessments, Multimodal Treatments, Individual Counseling, and Research in Germany, Austria, and Switzerland

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background The HIT network was established in 2000 to create a population‐based structure aiming to improve survival rates and reduce late effects for children with central nervous system (CNS) tumors by conducting comprehensive clinical trials.
Stefan Rutkowski, Michael C. Frühwald, Gudrun Fleischhack, Stephan Tippelt, Pablo Hernáiz‐Driever, Olaf Witt, Astrid Gnekow, Christof Kramm, Matthias Eyrich, Johannes E. A. Wolf, Hermann Müller, Carsten Friedrich, Uwe R. Kordes, Denise Obrecht‐Sturm, Petra Ketteler, Barbara von Zezschwitz, Pascal Johann, Dominik Sturm, Karoline Nemes, Stefan Schönberger, Till Milde, Brigitte Bison, Monika Warmuth‐Metz, Torsten Pietsch, Ulrich Schüller, Arend Koch, David Capper, Martin Hasselblatt, Christian Thomas, Christian Hagel, Stefan M. Pfister, Felix Sahm, David T. W. Jones, Martin U. Schuhmann, Jürgen Krauss, Pedram Emami, Ahmed El Damaty, Rolf D. Kortmann, Rudolf Schwarz, Jürgen Debus, Mechthild Krause, Fabian Pohl, Holger Ottensmeier, Lisa Bußenius, Katja Baust, Andreas Faldum, Cecile Ronckers, Desiree Grabow, Martin Benesch, Thomas Perwein, Karin Dieckmann, Irene Slavc, Johannes Gojo, Nicolas U. Gerber, André O. von Bueren, Katrin Scheinemann, Gabriele Calaminus, Beate Timmermann, Ulrich‐Wilhelm Thomale, Martin Mynarek   +59 more
wiley   +1 more source

Do all patients that undergo a ‘complete’ secondary cytoreductive surgery for platinum-sensitive recurrent ovarian cancer, benefit from it?

Pleura and Peritoneum
– Selection criteria used in all three randomized trials are predictive of a complete cytoreduction and not the benefit of surgery– Post-hoc & prespecified subgroup analyses indicate that not all patients undergoing secondary cytoreduction benefit from ...
Bhatt Aditi, Mehta Sanket, Glehen Olivier   +2 more
doaj   +1 more source

Optimizing Patient Selection for Irreversible Electroporation of Locally Advanced Pancreatic Cancer: Analyses of Survival

Frontiers in Oncology, 2022
BackgroundIrreversible electroporation (IRE) has emerged as a viable consolidative therapy after induction chemotherapy, in which this combination has improved overall survival of locally advanced pancreatic cancer (LAPC).
Matthew R. Woeste, Khaleel D. Wilson, Edward J. Kruse, Matthew J. Weiss, John D. Christein, Rebekah R. White, Robert C. G. Martin   +6 more
doaj   +1 more source

Stressful Events Reported by Childhood Cancer Survivors and Community Controls From the St. Jude Lifetime (SJLIFE) Cohort: A Mixed Method Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Characterizing stressful events reported by childhood cancer survivors experienced throughout the lifespan may help improve trauma‐informed care relevant to the survivor experience. Methods Participants included 2552 survivors (54% female; 34 years of age) and 469 community controls (62% female; 33 years of age) from the St.
Megan E. Ware, Colter K. Clayton, Fang Wang, Sedigheh Mirzaei, Kyla Shelton, Tara M. Brinkman, Victoria Willard, Katianne M. Howard Sharp, Kevin Krull, Lindsay F. Schwartz, Melissa M. Hudson, Gregory T. Armstrong, Kirsten K. Ness, Rachel T. Webster   +13 more
wiley   +1 more source