Outcome-Based Decision-Making Algorithm for Treating Patients with Primary Aldosteronism [PDF]
Background Optimal management of primary aldosteronism (PA) is crucial due to the increased risk of cardiovascular and cerebrovascular diseases. Adrenal venous sampling (AVS) is the gold standard method for determining subtype but is technically ...
Jung Hee Kim+11 more
doaj +1 more source
Towards Trustworthy Cross-patient Model Development [PDF]
Machine learning is used in medicine to support physicians in examination, diagnosis, and predicting outcomes. One of the most dynamic area is the usage of patient generated health data from intensive care units. The goal of this paper is to demonstrate how we advance cross-patient ML model development by combining the patient's demographics data with ...
arxiv
The current role of secondary cytoreductive surgery for recurrent ovarian cancer
Ovarian cancer represents worldwide the second most frequent and the most fatal gynecological malignancy, with approximately two thirds of the patients presenting with advanced disease. Cytoreductive surgery, primary or after neoadjuvant chemotherapy, in
Eelco de Bree+2 more
doaj +1 more source
Machine learning-based patient selection in an emergency department [PDF]
The performance of Emergency Departments (EDs) is of great importance for any health care system, as they serve as the entry point for many patients. However, among other factors, the variability of patient acuity levels and corresponding treatment requirements of patients visiting EDs imposes significant challenges on decision makers.
arxiv
Evaluating candidate reactions to selection practices using organisational justice theory [PDF]
Objectives: This study aimed to examine candidate reactions to selection practices in postgraduate medical training using organisational justice theory.
Carr, V.+4 more
core +1 more source
The relation between cardiac 123I-mIBG scintigraphy and functional response 1 year after CRT implantation [PDF]
Cardiac resynchronization therapy (CRT) is a disease-modifying therapy in patients with chronic heart failure (CHF). Current guidelines ascribe CRT eligibility on three parameters only: left ventricular ejection fraction (LVEF), QRS duration, and New ...
de Groot, J R+7 more
core +1 more source
Leveraging a Joint of Phenotypic and Genetic Features on Cancer Patient Subgrouping [PDF]
Cancer is responsible for millions of deaths worldwide every year. Although significant progress has been achieved in cancer medicine, many issues remain to be addressed for improving cancer therapy. Appropriate cancer patient stratification is the prerequisite for selecting appropriate treatment plan, as cancer patients are of known heterogeneous ...
arxiv
Combining Real-World and Randomized Control Trial Data Using Data-Adaptive Weighting via the On-Trial Score [PDF]
Clinical trials with a hybrid control arm (a control arm constructed from a combination of randomized patients and real-world data on patients receiving usual care in standard clinical practice) have the potential to decrease the cost of randomized trials while increasing the proportion of trial patients given access to novel therapeutics. However, due
arxiv
Patients with advanced hepatocellular carcinoma (HCC) have a very limited survival rate even after the recent inclusion of kinase inhibitors or immune checkpoint inhibitors in the therapeutic armamentarium. A significant problem with the current proposed
Elias Kouroumalis+2 more
doaj +1 more source
Liver Transplantation in Adults [PDF]
Human liver transplantation has been possible since 1967. We report our experience in 32 adult patients who received liver transplants at the University of Pittsburgh over a 16‐month period.
Dugas, M+6 more
core +1 more source