Results 61 to 70 of about 19,068,215 (411)

Recognising Bias in Studies of Diagnostic Tests Part 1: Patient Selection

open access: yesEmergency Medicine Journal, 2019
In this two-part series on sources of bias in studies of diagnostic test performance, we outline common errors and optimal conditions during three study phases: patient selection, interpretation of the index test and disease verification by a gold ...
M. K. Hall, B. Kea, Ralph C. Wang
semanticscholar   +1 more source

FoxO1 signaling in B cell malignancies and its therapeutic targeting

open access: yesFEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac   +3 more
wiley   +1 more source

Self-management support for chronic disease in primary care: frequency of patient self-management problems and patient reported priorities, and alignment with ultimate behavior goal selection. [PDF]

open access: yes, 2019
BackgroundTo enable delivery of high quality patient-centered care, as well as to allow primary care health systems to allocate appropriate resources that align with patients' identified self-management problems (SM-Problems) and priorities (SM ...
Bowyer, Vicky   +8 more
core   +1 more source

Current Management of Small Renal Masses, Including Patient Selection, Renal Tumor Biopsy, Active Surveillance, and Thermal Ablation.

open access: yesJournal of Clinical Oncology, 2018
Renal cancer represents 2% to 3% of all cancers, and its incidence is rising. The increased use of ultrasonography and cross-sectional imaging has resulted in the clinical dilemma of incidentally detected small renal masses (SRMs).
Alejandro Sanchez, A. Feldman, A. Hakimi
semanticscholar   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Limits to Patient Selection [PDF]

open access: yesAMA Journal of Ethics, 2011
Patients can use Internet sources to select physicians; physicians who use patient databases to select or reject patients, however, cross a professional-ethical boundary. Virtual Mentor is a monthly bioethics journal published by the American Medical Association.
openaire   +3 more sources

Surgical patient selection and counseling [PDF]

open access: yesTranslational Andrology and Urology, 2017
The objectives of patient selection and counseling are ultimately to enhance successful outcomes. However, the definition for success is often narrowly defined in published literature (ability to complete surgery, complications, satisfaction) and fails to account for patient desires and expectations, temporal changes, natural history of underlying ...
Tanner Miest   +5 more
openaire   +2 more sources

Photobiomodulation for the management of alopecia: mechanisms of action, patient selection and perspectives

open access: yesClinical, Cosmetic and Investigational Dermatology, 2019
Photobiomodulation (PBM) or low-level laser therapy was discovered over 50 years ago, when Mester in Hungary observed regrowth of hair in mice when irradiated with a ruby laser.
Michael R Hamblin
semanticscholar   +1 more source

Insights into the renal pathophysiology in Hermansky‐Pudlak syndrome‐1 from urinary extracellular vesicle proteomics and a new mouse model

open access: yesFEBS Letters, EarlyView.
Hermansky‐Pudlak syndrome type 1 (HPS‐1) is a rare, autosomal recessive disorder with poorly understood renal involvement. Urinary extracellular vesicle (uEV) proteomics and a novel Hps1 mouse model reveal mitochondrial abnormalities and lipid accumulation in HPS‐1 kidney proximal tubule cells. Serum ApoA1 correlates with kidney function in our patient
Dawn M. Maynard   +7 more
wiley   +1 more source

Fractional Flow Reserve: Patient Selection and Perspectives

open access: yesVascular Health and Risk Management, 2021
Joyce Peper,1,2,* Leonie M Becker,1,2,* Jan-Peter van Kuijk,1 Tim Leiner,2 Martin J Swaans1 1Department of Cardiology, St. Antonius Hospital, Nieuwegein, The Netherlands; 2Department of Radiology, University Medical Center Utrecht, Utrecht, The ...
Peper J   +4 more
doaj  

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