Results 201 to 210 of about 1,390,378 (262)

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Deciphering the lactylation landscape in glioma: a novel gene signature predicts patient survival and immunotherapy sensitivity. [PDF]

Front Immunol
Tang X, Liu Y, Yang C, Zhang H, Zhang G, Wang Q, Jiang S, Gao X, Liu Y, Dong Y.   +9 more
europepmc   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Editorial Expression of Concern: Overexpression of miR-26a-2 in human liposarcoma is correlated with poor patient survival. [PDF]

Oncogenesis
Lee DH, Amanat S, Goff C, Weiss LM, Said JW, Doan NB, Sato-Otsubo A, Ogawa S, Forscher C, Koeffler HP.   +9 more
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Ectopic HLA-II Expression in ESCC: Exploration of Its Relationship with Neoantigen Burden and Patient Survival. [PDF]

Cells
Ji Y, Wang Z, Cheng Z, Lu S, Lemoine NR, Baleeiro R, Dunmall LSC, Wang Y.   +7 more
europepmc   +1 more source

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

Predicting Grade and Patient Survival in Renal Cancer Using Machine Learning Analysis of Nucleolar Prominence. [PDF]

Cancer Med
Ivanova E, Fayzullin A, Grinin V, Zhavoronkov D, Ermilov D, Balyasin M, Timakova A, Bakulina A, Osmanov Y, Rudenko E, Arutyunyan A, Parchiev R, Shved N, Astaeva M, Lychagin A, Demura T, Timashev P.   +16 more
europepmc   +1 more source

Distinct cerebrospinal fluid proteomic signatures define clinicopathological subtypes of sporadic Creutzfeldt-Jakob disease and predict patient survival. [PDF]

Acta Neuropathol Commun
Bentivenga GM, Mammana A, Gogishvili D, Baiardi S, Vittoriosi E, Mastrangelo A, Ranieri A, Houtkamp IM, Brockmann K, Abeln S, Capellari S, Parchi P.   +11 more
europepmc   +1 more source

Improving the Compliance of Massive Hemorrhage Protocols Through Education Is Associated with Patient Survival. [PDF]

J Clin Med
Paniagua-Iglesias P, Rincón-Ferrari MD, Candela-Toha A, Marcos-Jubilar M, Barquero-Lopez M, Gich-Saladich I, Medina-Marrero L, Bosch-Llobet A, Garrido-Fleischmann D, Ordoñez-Llanos J, Urrutia-Cuchí G.   +10 more
europepmc   +1 more source