Results 51 to 60 of about 5,573,253 (313)

Effect of time delay in inter-hospital transfer on outcomes of endovascular treatment of acute ischemic stroke

open access: yesFrontiers in Neurology, 2023
BackgroundEndovascular treatment (EVT) with mechanical thrombectomy is the standard of care for large vessel occlusion (LVO) in acute ischemic stroke (AIS).
Keshet Pardo   +15 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Caracterización de los traslados médicos no regulados desde diferentes instituciones prestadoras de salud hacia el Hospital Pablo Tobón Uribe de Medellín, en el año 2017

open access: yesMedicina U.P.B., 2019
Objetivo: los trasladosno regulados son aquellos en los que se transfieren pacientes a instituciones prestadoras de salud (IPS) de mayor complejidad, en búsqueda de re-cursos y que, por motivos administrativos o propios del transferido, se requieren con ...
Jaime Andrés Giraldo Hoyos   +3 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Patient Experience: The field and future [PDF]

open access: yes, 2017
In an effort to understand the progress and evolution of the field, a self-examination study has been administered to assess contributions to the core knowledge base in the field and to assess the degree to which articles published in Patient Experience ...
Haun, Courtney N., MPH   +2 more
core   +1 more source

Prevalence and Factors Associated with Musculoskeletal Disorders among Thai Hospital Orderlies

open access: yesInternational Journal of Occupational Hygiene, 2015
Musculoskeletal problems, resulting from lifting and transferring patients, are often reported among hospital orderlies worldwide. The purpose of this study was to describe the prevalence and factors associated with musculoskeletal disorders in Thai ...
WITHAYA CHANCHAI   +4 more
doaj  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Designing for Improving Verbal Patient Transfer [PDF]

open access: yes, 2009
The current verbal patient transfer between nurses and paramedics lacks communication, which leads to loss of information. During this operation, handwritten protocols are used to document the patient’s personal data and the treatment given at several intervals. In order to encourage teamwork between the two parties (i.e.
Abdullah Al Mahmud 0001   +2 more
openaire   +3 more sources

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

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