Results 1 to 10 of about 257,507 (70)

Gene Therapy in Hemophilia: A Transformational Patient Experience

open access: yesJournal of Patient Experience, 2023
Hemophilia is a bleeding disorder caused by a single absent/defective gene and characterized by a lack of functional clotting factors. People with hemophilia may experience joint damage, pain, and psychological impairments, all of which could contribute ...
Enayet Rasul   +7 more
doaj   +1 more source

Rapidly Switchable Universal CAR-T Cells for Treatment of CD123-Positive Leukemia

open access: yesMolecular Therapy: Oncolytics, 2020
Chimeric antigen receptor T cells (CAR-T) targeting CD19 or B cell maturation antigen (BCMA) are highly effective against B cell malignancies. However, application of CAR-T to less differentially expressed targets remains a challenge due to lack of tumor-
Simon Loff   +13 more
doaj   +1 more source

Improving Access and Mental Health For Youth Using Smart Technologies

open access: yesIET Smart Cities, 2021
The overall objective of this research is to evaluate the use of a mobile health smartphone application (app) to improve the mental health of youth between the ages of 14 and 25 years, with symptoms of anxiety and/or depression. This project includes 122
Cheryl Forchuk   +11 more
doaj   +1 more source

Spinal cord stimulation for the relief of spasticity from cerebral palsy

open access: yesHealthcare Technology Letters, 2020
Cerebral palsy (CP) is the most common form of childhood disability, and spasticity is the most common motor-manifestation. Thankfully, there has been a significant reduction in the percentage of children born with CP in recent years, but nonetheless ...
John Parker, Birte Elisabeth Dietz
doaj   +1 more source

Optimal control methods for drug delivery in cancerous tumour by anti‐angiogenic therapy and chemotherapy

open access: yesIET Systems Biology, 2021
There are numerous mathematical models simulating the behaviour of cancer by considering variety of states in different treatment strategies, such as chemotherapy.
Pariya Khalili   +3 more
doaj   +1 more source

Contralaterally EMG-triggered functional electrical stimulation during serious gaming for upper limb stroke rehabilitation: a feasibility study

open access: yesFrontiers in Neurorobotics, 2023
IntroductionVirtual Reality/serious games (SG) and functional electrical stimulation (FES) therapies are used in upper limb stroke rehabilitation. A combination of both approaches seems to be beneficial for therapy success.
Chiara Höhler   +7 more
doaj   +1 more source

Severity detection tool for patients with infectious disease

open access: yesHealthcare Technology Letters, 2020
Hand foot and mouth disease (HFMD) and tetanus are serious infectious diseases in low- and middle-income countries. Tetanus, in particular, has a high mortality rate and its treatment is resource-demanding.
Girmaw Abebe Tadesse   +18 more
doaj   +1 more source

Assessment of inflow and outflow stenoses using big spectral data and radial-based colour relation analysis on in vitro arteriovenous graft biophysical experimental model

open access: yesIET Cyber-Physical Systems, 2017
Dialysis vascular accesses are critical for dialysis therapy, but they frequently suffer from stenotic complications. Higher patency rates and thrombosis rates are a concern to nephrology nurses and patients.
Wei-Ling Chen   +2 more
doaj   +1 more source

Spinal cord stimulation for the restoration of bladder function after spinal cord injury

open access: yesHealthcare Technology Letters, 2020
Spinal cord injury (SCI) results in the inability to empty the bladder voluntarily, and neurogenic detrusor overactivity (NDO) and detrusor sphincter dyssynergia (DSD) negatively impact both the health and quality of life of persons with SCI.
Casey J. Steadman, Warren M. Grill
doaj   +1 more source

Non‐invasive ventilation treatment for patients with chronic obstructive pulmonary disease

open access: yesHealthcare Technology Letters, 2023
Chronic obstructive pulmonary disease (COPD) affects the lives of millions of patients worldwide. Patients with advanced COPD may require non‐invasive ventilation (NIV) to support the resultant deficiencies of the respiratory system.
Fleur T. Tehrani, James H. Roum
doaj   +1 more source

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