Results 121 to 130 of about 429,116 (360)

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Nurses\u27 Alumnae Association Bulletin - Volume 17 Number 1 [PDF]

, 1952
Alumnae Notes Committee Reports Digest of Alumnae Association Meetings Greetings from Miss Childs Greetings from the Educational Director Greetings from the President Graduation Awards - 1951 Jefferson\u27s New Hospital Addition Marriages Necrology ...
Alpers, Bernard J, Boerlin, Paully Jane, Childs, Katherine, Cozza, Angela R, Flack, Herbert L, Flanagan, Jeanne, Hamrick, Hayward R, Kevel, Isabelle, Kuba, Anna, Miller, Franklin R, Nentwig, Dorothy, Piersol, Betty, Plaisted, Marilyn, Skvir, Elsie, Spruance, Henrietta Fitzgerald, Whitney, Helen M, Yaeger, Rudolph, Zeldis, William   +17 more
core   +1 more source

Exploring Age-appropriate Design Attributes of Hospital Activity Rooms for Adolescent Patients

, 2023
Eun Young Kim
openalex   +2 more sources

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Nurses’ perceptions of the transition to 100% single-occupancy patient rooms in a university hospital in the Netherlands: an uncontrolled before and after study

BMC Nursing
Background To improve patients’ privacy, comfort and infection control, newly built hospitals increasingly offer 100% single-occupancy patient rooms. Our study examines how nurses perceived the transition from a hospital with multi-bedded patient rooms ...
Ralph Pruijsten, Erwin Ista, Jill Maben, Liesbeth van Heel, Monique van Dijk   +4 more
doaj   +1 more source

Environmental contamination in the isolation rooms of COVID-19 patients with severe pneumonia requiring mechanical ventilation or high-flow oxygen therapy [PDF]

, 2020
Jin Young Ahn, Susun An, Young H. Sohn, Yeona Cho, Jong Hoon Hyun, Y.J. Baek, Myoung Hwa Kim, Su Jin Jeong, Jung Ho Kim, Nam Su Ku, Joon‐Sup Yeom, Davey M. Smith, Hyukmin Lee, Dongeun Yong, Yong‐Jae Lee, Jungwon Kim, Hyung Rae Kim, Jungho Hwang, Jun Yong Choi   +18 more
openalex   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Effect of single-patient room design on the incidence of nosocomial infection in the intensive care unit: a systematic review and meta-analysis

Frontiers in Medicine
BackgroundPrevious studies have yielded varying conclusions regarding the impact of single-patient room design on nosocomial infection in the intensive care unit (ICU). We aimed to examine the impact of ICU single-patient room design on infection control.
Zheng Zhang, Xiaojiao Tan, Haiqing Shi, Jia Zhao, Jia Zhao, Huan Zhang, Huan Zhang, Jianbo Li, Xuelian Liao, Xuelian Liao   +9 more
doaj   +1 more source

Barnes Hospital Bulletin [PDF]

, 1974
https://digitalcommons.wustl.edu/bjc_barnes_bulletin/1102/thumbnail ...

core   +1 more source

The effectiveness of hepa filtered rooms plus fluconazol prophylaxis for preventation of invasive fungal diseases in allogenic stem cell transplant patients [PDF]

, 2015
C Altay Kurkcuoglu, Gökhan Metan, Leylagül Kaynar, Ferhan Elmalı, Emine Alp, Mustafa Çetın   +5 more
openalex   +1 more source