Results 41 to 50 of about 4,286,367 (298)

Gut dysbiosis induces the development of depression-like behavior through abnormal synapse pruning in microglia-mediated by complement C3

Microbiome
Background Remodeling eubiosis of the gut microenvironment may contribute to preventing the occurrence and development of depression. Mounting experimental evidence has shown that complement C3 signaling is associated with the pathogenesis of depression,
Wenzhi Hao, Qingyu Ma, Lu Wang, Naijun Yuan, Hua Gan, Liangliang He, Xiaojuan Li, Junqing Huang, Jiaxu Chen   +8 more
doaj   +1 more source

Learning to Recognize Chest-Xray Images Faster and More Efficiently Based on Multi-Kernel Depthwise Convolution

IEEE Access, 2020
The development of convolutional neural networks has promoted the progress of computer-aided diagnostic systems. Details in medical image, such as the texture and tissue structure, are crucial features for diagnosis.
Mengjie Hu, Hezheng Lin, Zimeng Fan, Wenjie Gao, Lu Yang, Chun Liu, Qing Song   +6 more
doaj   +1 more source

Integrating Clinical and Genomic Analyses of Hippocampal-Prefrontal Circuit Disorder in Depression

Frontiers in Genetics, 2021
Major depressive disorder (MDD) is a prevalent, devastating and recurrent mental disease. Hippocampus (HIP)-prefrontal cortex (PFC) neural circuit abnormalities have been confirmed to exist in MDD; however, the gene-related molecular features of this ...
Naijun Yuan, Kairui Tang, Xiaoli Da, Hua Gan, Liangliang He, Liangliang He, Xiaojuan Li, Qingyu Ma, Jiaxu Chen, Jiaxu Chen   +9 more
doaj   +1 more source

Patterns of Patterns II

, 2023
Our earlier paper "Patterns of Patterns" combined three techniques from training, futures studies, and design in a design pattern called PLACARD that helps groups of people work together effectively. We used that pattern in five hands-on workshop case studies which took place at various locations in the US and the UK.
Corneli, Joseph, Alhasan, Noorah, Vivier, Leo, Murphy, Alex, Puzio, Raymond S., Tabor, Abby, Ayloo, Sridevi, Pierce, Charlotte, Danoff, Charles J., Tedeschi, Mary, Singh, Manvinder, Khetan, Kajol   +11 more
openaire   +2 more sources

Stereotactic Body Radiation Therapy for Pediatric, Adolescent, and Young Adult Patients With Osteosarcoma: Local Control Outcomes With Dosimetric Analysis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Osteosarcoma is a radioresistant tumor that may benefit from stereotactic body radiation therapy (SBRT) for locoregional control in metastatic/recurrent disease. We report institutional practice patterns, outcomes, toxicity, and failures in osteosarcoma patients treated with SBRT.
Jenna Kocsis, Shauna R. Campbell, Jonathan Jang, Eashwar Somasundaram, Chandana A. Reddy, Jacob G. Scott, Lilyana Angelov, Peter M. Anderson, Matteo Trucco, Zachary Burke, Lukas Nystrom, Nathan Mesko, Anthony Magnelli, Erin S. Murphy   +13 more
wiley   +1 more source

Lifestyle Behaviors and Cardiotoxic Treatment Risks in Adult Childhood Cancer Survivors

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Higher doses of anthracyclines and heart‐relevant radiotherapy increase cardiovascular disease (CVD) risk. This study assessed CVD and CVD risk factors among adult childhood cancer survivors (CCSs) across cardiotoxic treatment risk groups and examined associations between lifestyle behaviors and treatment risks.
Ruijie Li, Raquel Revuelta Iniesta, Alan R. Barker, Dimitris Vlachopoulos, Tomáš Sláma, Christina Schindera, Fabiën N. Belle   +6 more
wiley   +1 more source

A Novel Framework for Interactive Visualization and Analysis of Hyperspectral Image Data

Journal of Electrical and Computer Engineering, 2016
Multispectral and hyperspectral images are well established in various fields of application like remote sensing, astronomy, and microscopic spectroscopy.
Johannes Jordan, Elli Angelopoulou, Andreas Maier   +2 more
doaj   +1 more source

Cerebrospinal Fluid Liquid Biopsy Enables Targeted Therapy Without Tissue Diagnosis in Pediatric Low‐Grade Gliomas With BRAF V600E Mutation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT We present two pediatric cases of pediatric low‐grade gliomas (PLGG) with BRAF V600E mutations diagnosed and monitored using cerebrospinal fluid (CSF) liquid biopsy analyzed via digital droplet PCR (ddPCR), without tissue biopsy. Both patients were treated with dabrafenib and trametinib and monitored through clinical assessments, magnetic ...
Hannah Sultan, Damien Faury, Alexander G. Weil, Harrison J. Westwick, Nada Jabado, Sébastien Perreault   +5 more
wiley   +1 more source

The changing alcohol drinking patterns among older adults show that women are closing the gender gap in more frequent drinking: the Tromsø study, 1994–2016 [PDF]

, 2021
Line Tegner Stelander, Anne Høye, Jørgen G. Bramness, Geir Selbæk, Linn-Heidi Lunde, Rolf Wynn, Ole Grønli   +6 more
openalex   +1 more source

Changes in Body Composition in Children and Young People Undergoing Treatment for Acute Lymphoblastic Leukemia: A Systematic Review and Meta‐Analysis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Ongoing evidence indicates increased risk of sarcopenic obesity among children and young people (CYP) with acute lymphoblastic leukemia (ALL), often beginning early in treatment, persisting into survivorship. This review evaluates current literature on body composition in CYP with ALL during and after treatment.
Lina A. Zahed, Raquel Revuelta Iniesta, Mary Fewtrell, Julie Lanigan, Breeana Gardiner, Graeme O'Connor   +5 more
wiley   +1 more source