Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
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Contrast-enhanced ultrasound enhancement-pattern classification for procedure selection and perioperative outcomes in cesarean scar pregnancy. [PDF]
Front SurgYang J, Xu Z, Liu X, Feng J, Niu Y.
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Pattern Classification of Hand Movement Tremor in MS Patients with DBS ON and OFF. [PDF]
J Biomed Phys Eng, 2022 Valipour F, Esteki A.
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Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
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Combination of features from skin pattern and ABCD analysis for lesion classification [PDF]
Background/Purpose: It is known that the standard features for lesion classification are ABCD features, that is, asymmetry, border irregularity, colour variegation and diameter of lesion.
Liu, Y, She, Zhishun, Damatoa, A
core
Exploring potential of Turing pattern classification through convolution maps. [PDF]
Sci RepShin J, Park J, Ji M, Lee S.
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Villoglandular Pattern in HPV-associated Endocervical Adenocarcinoma is Associated With Excellent Prognosis: A Reappraisal of 31 Cases Using IECC and Silva Pattern Classification. [PDF]
Int J Gynecol Pathol, 2023 Stolnicu S +14 more
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ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
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The Utilization of a Gait Pattern Classification System to Investigate the Effects of Ankle-Foot Orthoses on Gait in Children with Cerebral Palsy. [PDF]
Children (Basel)Goihl T +3 more
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Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
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