Results 161 to 170 of about 11,592,948 (265)
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Flounced frock with ribbon and lace trim, 1919
Pattern No. 4654: Sleeves are "slashed and trimmed with wide bands of lace and ribbon." Collar is gathered and trimmed with a tiny ribbon bow. Shirtwaist and skirt panel are trimmed with wide bands of lace and tiny ribbon bows.
Vogue Pattern Service
core
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Envelope for a Simplicity pattern to make a Misses' topper jacket with bias shawl collar and raglan sleeves, including illustrations of the finished pieces and information about sizing and construction on the ...
Simplicity Pattern Co.
core +1 more source
Pattern No. 3805: Shirtwaist with a rolled collar faced in wide lace and a square-necked vest with wide lace along the upper half. Sleeves are "cut with a shaped cap to which is shirred the lower section of the sleeve, which is finished by a tight ...
Vogue Pattern Service
core
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Coat-frock with waistcoat, 1919
Pattern No. 4780: Waistcoat is trimmed along the edges with braid and down the center with a row of small buttons. Lower edge of the collared, belted blouse "turns up to form a deep cuff which is held in place at the center back with three buttons." Bell-
Vogue Pattern Service
core
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Blouse, Skirt and Culotte Ensemble
Butterick pattern to make a Misses' blouse with band collar and kimono sleeves, flared skirt and culotte, including illustrations of the finished pieces and information about sizing and construction on the ...
Aimbez, Gil
core

