Results 151 to 160 of about 13,306,677 (316)

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Belted skirt with tunic and shirtwaist; and, frock with wrapped tunic, 1919

, 1919
Pattern No. 4538-39: Shirtwaist with decorative front panel and sleeves "slightly flared at the wrist." Hobble skirt with decorative belt and tunic that flows from the hips. Accessorized with a beret-like hat with a pompom. Pattern No.
Vogue Pattern Service
core  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Nightgown, 1919

, 1919
Pattern No. 4709: Square-necked nightgown with a yoke "trimmed with small tucks and an applied box plait at the center front." Sleeves are "gathered and finished at the lower edge with a narrow ruffle of lace." Gown is "trimmed with ruffles of narrow ...
Vogue Pattern Service
core  

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Individualist

, 1987
Vogue Individualist Pattern #1905 by Tomatsu to make a dress with a collar, dropped shoulders, shoulder pads, blouson bodice with pleats, pockets, and flared skirt, including illustrations of the finished pieces and information about sizing and ...
Tomatsu, Vogue Pattern Service
core  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Jacket

, 1980
Envelope for a Butterick "Fast & Easy" pattern to make a Misses short bolero style or long waisted jacket with cardigan style neckline, including illustrations of the finished pieces and information about sizing and construction on the ...
Butterick Pattern Service
core  

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Sea ice pattern effect on Earth's energy budget is characterized by hemispheric asymmetry. [PDF]

Sci Adv
Zhou C, Wang Q, Tan I, Zhang L, Zelinka MD, Wang M, Bloch-Johnson J.   +6 more
europepmc   +1 more source