Results 171 to 180 of about 13,310,515 (316)

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Surplice frock, 1920

open access: yes, 1920
Pattern No. 4306: Collared surplice shirtwaist with a narrow girdle that is drawn through slashes at either side and fastens at the left side with a button; girdle is trimmed with embroidery. Sleeves are "darted from the lower edge to fit the arm snugly,
Vogue Pattern Service
core  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Misses afternoon frock; and, kimona shirtwaist with straight plaited skirt, 1917

open access: yes, 1917
Pattern No. 3653: Shirtwaist that crosses surplice fashion at the front and has sleeves which are "gathered into small trimming bands at the wrists." Narrow collar is drawn through slashes at each side of the center front and straps are buttoned over the
Vogue Pattern Service
core  

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Tailored shirtwaist with separate skirt, 1914

open access: yes, 1914
Pattern No. 2498: Tailored shirtwaist with a wide collar trimmed with a ruffle and finished with a box. Shirtwaist buttons up the front center. Sleeves are finished with a turned-back cuff fastened with a linked button and trimmed with a ruffle ...
Vogue Pattern Service
core  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

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