Results 171 to 180 of about 13,292,654 (316)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Dress

, 1986
Envelope for a Simplicity pattern to make a Misses' size dress in five sheath and dropped waist styles, including illustrations of the finished pieces and information about sizing and construction on the ...
Simplicity Pattern Co.
core  

When orcas hit the rudder: what Iberian orca-boat interactions reveal about action explanations in animal cognition. [PDF]

Anim Cogn
Frings C.
europepmc   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Misses afternoon frock; and, kimona shirtwaist with straight plaited skirt, 1917

, 1917
Pattern No. 3653: Shirtwaist that crosses surplice fashion at the front and has sleeves which are "gathered into small trimming bands at the wrists." Narrow collar is drawn through slashes at each side of the center front and straps are buttoned over the
Vogue Pattern Service
core  

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Tailored shirtwaist with separate skirt, 1914

, 1914
Pattern No. 2498: Tailored shirtwaist with a wide collar trimmed with a ruffle and finished with a box. Shirtwaist buttons up the front center. Sleeves are finished with a turned-back cuff fastened with a linked button and trimmed with a ruffle ...
Vogue Pattern Service
core  

Comorbidity patterns and risk of breast cancer: a case-control study exploring interaction with BMI using latent class analysis. [PDF]

Front Oncol
Zhang Y, Zhao B, Zhang X, Cui N, Wu L, Chen L.   +5 more
europepmc   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Sports suit, 1919

, 1919
Pattern No. 4801: Coat with revered shawl collar is fastened in front with a cord and buttons. Horseshoe pockets are "finished at the corners with embroidered arrows and fastened with buttons." Sleeves are buttoned at the wrist.
Vogue Pattern Service
core