Results 251 to 260 of about 13,306,677 (316)

Comment on "Symptom Clusters and Frailty Among Older Adults With and Without Cancer: Insights From Two Cross-Sectional Studies". [PDF]

Nurs Health Sci
Desai S, Malik MMUD.
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Temporal binding and social perception - A replication study. [PDF]

PLoS One
Vogel DHV, Woschei M, Jording M, Weiss PH, Vogeley K.   +4 more
europepmc   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Ketamine Across the Dose-State Continuum: EEG Signatures, Network Dynamics, and Implications for Brain-State Monitoring in Anesthesia and Critical Care. [PDF]

Brain Sci
Chauhan V, Khan F.
europepmc   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Whole-Genome Resequencing Reveals Selection Signatures Associated With Lambskin Patterns in Hu Sheep. [PDF]

Anim Genet
Beshah KH, Xie J, Tariq M, Quddus A, Wang D, Zhao B, Mao D.   +6 more
europepmc   +1 more source

Modulation of the rumen microbiome and metabolism in dairy cows by altering the concentrate feeding pattern and the inclusion of <i>Saccharomyces cerevisiae</i> yeast. [PDF]

Front Microbiomes
Snelling TJ, Johnson CA, Warren HE, Taylor-Pickard J, Huntington JA, Sinclair LA.   +5 more
europepmc   +1 more source

Flexible Coding of Morpheme Position Information in Tibetan Reading: Evidence from Eye Movements. [PDF]

Behav Sci (Basel)
Li S, Zhang C, Gao L, Wang C, Gao X.
europepmc   +1 more source

Prognostic role of endometrial pattern compared with thickness and estradiol in euploid HRT-FET cycles. [PDF]

Front Med (Lausanne)
Peker N, Yücetürk A, Tığlı E, Karaosmanoğlu Ö, Elmas B, Özer Aslan İ, Tıraş B.   +6 more
europepmc   +1 more source