Results 181 to 190 of about 3,504,331 (315)

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Robust and resource-optimal dynamic pattern formation of Min proteins in vivo. [PDF]

Nat Phys
Ren Z, Weyer H, Sandler M, Würthner L, Fu H, Tangtartharakul CB, Li D, Sou C, Villarreal D, Kim JE, Frey E, Jun S.   +11 more
europepmc   +1 more source

Forceful patterning: theoretical principles of mechanochemical pattern formation. [PDF]

EMBO Rep, 2023
Rombouts J, Elliott J, Erzberger A.
europepmc   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Electrically Guided Deposition of Electrospun Nanofibers for Fiber and Cell Pattern Formation. [PDF]

Macromol Biosci
Yan Z, Xie J.
europepmc   +1 more source

Study of biofilm formation and antibiotic resistance pattern of gram-negative Bacilli among the clinical isolates at BPKIHS, Dharan [PDF]

, 2019
Rabina Dumaru, Ratna Baral, Lok Bahadur Shrestha   +2 more
openalex   +1 more source

Pattern Formation [PDF]

, 2020
openaire   +2 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Corrigendum: Correspondences Between Parameters in a Reaction-Diffusion Model and Connexin Function During Zebrafish Stripe Formation

Frontiers in Physics, 2022
Akiko M. Nakamasu
doaj   +1 more source

Replay of Stimulus-specific Temporal Patterns during Associative Memory Formation [PDF]

, 2018
Sebastian Michelmann, Howard Bowman, Simon Hanslmayr   +2 more
openalex   +1 more source