Results 251 to 260 of about 1,415,133 (306)

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Turing pattern formation on the sphere is robust to the removal of a hole. [PDF]

J Math Biol
Borgqvist JG, Gerlee P, Lundholm C.
europepmc   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Artificial cell system as a tool for investigating pattern formation mechanisms of intracellular reaction-diffusion waves. [PDF]

Biophys Physicobiol
Takada S, Fujiwara K.
europepmc   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

Lattice Model Results for Pattern Formation in a Mixture with Competing Interactions. [PDF]

Molecules
De Virgiliis A, Meyra A, Ciach A.
europepmc   +1 more source

Emergence of non-trivial solutions from trivial solutions in reaction-diffusion equations for pattern formation. [PDF]

Math Biosci
Zhao XE, Hao W.
europepmc   +1 more source

Autophagy-mediated degradation of integumentary tapetum is critical for embryo pattern formation. [PDF]

Nat Commun
Zhao LL, Chen R, Bai Z, Liu J, Zhang Y, Zhong Y, Sun MX, Zhao P.   +7 more
europepmc   +1 more source

Pattern formation along signaling gradients driven by active droplet behaviour of cell groups

Ford HZ, Celora GL, Westbrook ER, Dalwadi MP, Walker BJ, Baumann H, Weijer CJ, Pearce P, Chubb JR.   +8 more
europepmc   +1 more source

Pulsed Interaction Signals as a Route to Biological Pattern Formation

Physical Review Letters, 2023
We identify a mechanism for biological spatial pattern formation arising when the signals that mediate interactions between individuals in a population have pulsed character.
E H Colombo, Cristobal Lopez, Emilio Hernández-García   +2 more
exaly   +3 more sources