Results 121 to 130 of about 4,604 (260)

Pericentrosomal Redistribution of the Endoplasmic Reticulum Ensures Organelle Symmetric Inheritance and Mitotic Progression

Advanced Science, EarlyView.
Upon mitotic entry, RTN4 relocalizes to the pericentrosomal region, forming a more tubular ER network around centrosomes. CDK1‐mediated phosphorylation of RTN4 increases its interaction with Rab11 GTPase, facilitating dynein‐dependent transport of RTN4 to the pericentrosomal region.
Xiangyu Xu, Yalin Liu, Rongyi Wang, Wenwen Xu, Hao Shi, Ning Huang, Junlin Teng, Jin Meng, Pengli Zheng, Jianguo Chen   +9 more
wiley   +1 more source

Evaluation of Static and Dynamic Pupil and Light Sensitivity to a Single Drop of Various Concentrations of Low-Dose Atropine (0.01%, 0.025%, and 0.05%)

Life
This study aimed to evaluate the static and dynamic pupil changes, and light sensitivity following a single dose of low-dose atropine at concentrations of 0.01%, 0.025%, and 0.05% over a 24 h period.
Muteb K. Alanazi, Abdulmalik Almansour, Sarah S. Almutairi, Ahmad Alharbi, Mohammed S. Alhazmi, Ali Almustanyir, Basal H. Altoaimi, Meznah S. Almutairi, Mona M. Alamri, Maria Liu   +9 more
doaj   +1 more source

Association between cortical hyperexcitability and visual disturbances – evidence from behaviour and electroencephalogram [PDF]

, 2019
This thesis presents four studies that sought to examine the presence and role of cortical hyperexcitability underlying aberrant / anomalous perceptions in neurotypical and self-reported migraine groups.
Fong, Chun Yuen
core  

Targeting WDR12 Unleashes T‐Cell‐Mediated Antitumor Activity in Melanoma by Destabilizing CD276

Advanced Science, EarlyView.
WDR12 cooperates with the chaperonin subunit CCT7 to maintain CD276 stability on tumor cells, suppressing T‐cell activity and promoting immune escape. SU14813, a small‐molecule WDR12 inhibitor, reduces CD276 stability and relieves CD276‐mediated T‐cell suppression.
Jie Pan, Ruimin Chang, Meng Zhang, Qian Dong, Guanxiong Zhang, Xiang Chen, Mingliang Chen, Lixia Lu, Xiaowei Liang, Yeye Guo, Juan Su   +10 more
wiley   +1 more source

Glare, Daylight and View:“Exploratory study of the effect of patterns on glare and view in an indoor environment.”

, 2019
The dilemma of keeping the daylight quality and view to the outside or protecting our eyes from disturbing glare by covering the window is a moment that probably everyone has experienced in their life. Having access to daylight and enjoying the view to the outside when there is not visual comfort has been a problematic issue related to the window in ...
openaire   +1 more source

Evaluation of Discomfort Glare and Pavement Marking Material Visibility for Eleven Headlamp Configurations

, 2003
This research effort focused on ascertaining the headlamp technology (of the eleven specified) that minimized the amount of discomfort glare and maximized the visibility of three types of pavement marking materials used in the study.
Binder, Stephanie Colleen
core  

A Machine Vision‐Guided Microphysiological Platform With Automated Microfluidics Enables Longitudinal Biomarker Monitoring and Emulation of Translationally Relevant Exposure Scenarios

Advanced Science, EarlyView.
A pneumatically actuated multi‐tissue microphysiological system is integrated with AI‐based machine vision and automatic sampling and replenishment systems. The platform allows for the emulation of translationally relevant long‐term pharmacokinetic exposure scenarios for multiple weeks while enabling longitudinal monitoring of response biomarkers ...
Jibbe Keulen, Yi Zhong, Laura Dangel, Sonia Youhanna, Reza Zandi Shafagh, Jinhye Ryu, Domnica‐Gabriela Gurau, Mathias Haag, Thomas E. Mürdter, Yingxin Liang, Iro Beligiani, Nicole Ziegler, Sabine Willems, Nayere Taebnia, Wouter van der Wijngaart, Volker M. Lauschke   +15 more
wiley   +1 more source

An assessment on glare from daylight through various design of shading devices in hot humid climate, case study in Kuala Lumpur, Malaysia

, 2014
Glare is one of the main problems that cause daylight to be visually undesirable in a hot humid country such as Malaysia. However, the design of modern buildings in Malaysia applies large glass windows and some partially covered with various design of ...
Denan, Zuraini, Abdul Majid, Noor Hanita
core  

Material‐Encoded Synchronization of Immunogenic Cell Death With Adenosine A2A Receptor Blockade Reprograms the Tumor Microenvironment

Advanced Science, EarlyView.
A bismuth–copper diselenide–based nanoplatform (BSCS@PHY) coordinates immunogenic cell death with local A2A receptor blockade in 4T1 tumors. Thermally triggered shell melting exposes catalytic surfaces for glutathione depletion and chemodynamic ROS generation, while co‐delivering an A2AR antagonist and yeast‐wall adjuvant to enhance dendritic‐cell ...
Xiangting Yi, Hanlou Yang, Junting Huang, Pengfei Wu, Shiying Zhou, Zunde Liao, Min Han, Zishan Chen, Xiaoyu Huang, Nan Ma, Jie Zhou, Mingqiang Li, Yiling Zhong   +12 more
wiley   +1 more source

High‐Performance Transparent Solid Polymer Electrolyte Based on Copolymer of Deep Eutectic Electrolyte and Methyl Methacrylate for Electrochemical Devices

Advanced Science, EarlyView.
A copolymerization strategy using a polymerizable deep eutectic electrolyte with MMA forms efficient ion‐transport pathways while maintaining excellent transparency. The solid polymer electrolyte simultaneously achieves 17.8 MPa mechanical strength and 1.43 mS cm−1 ionic conductivity, enhancing long‐term cycling stability in Li|LFP batteries and ...
Tingting Chen, Sijia Han, Likun Wang, Sainan Ma, Liping Zhang, Yong Liu, Gaorong Han   +6 more
wiley   +1 more source