Results 121 to 130 of about 45,818 (266)
Why do words jump? An exploration of visually symptomatic readers
British and Irish Orthoptic Journal, 2012 Aim: To provide an insight into the current issues in assessing visually symptomatic readers and the role of the orthoptist in the management of these patients. Methods: A literature-based review was undertaken to investigate the assessment of patients
Nadia Northway
doaj +1 more source
, 2007 We investigate the mass function in the substellar domain down to a few Jupiter masses in the young sigma Orionis open cluster (3+/-2 Ma, d = 360^+70_-60 pc).
Allard +111 more
core +3 more sources
Advanced Science, EarlyView.This study established an RT‐MSCs‐based therapeutic approach for scleroderma in mice. RT‐MSCs attenuated fibrosis by regulating mitochondrial autophagy and restored gut microbiota homeostasis. Metabolomic analyses confirmed recovery of key metabolites, and RT‐MSCs demonstrated favorable lesion targeting and safety profiles.
Xue Xia +5 more
wiley +1 more source
Advanced Science, EarlyView.A healthy gut barrier shields underlying fibroblasts from luminal shear forces, illustrating that “good fences make good neighbors.” Barrier damage exposes fibroblasts to shear stress, inducing cell death and the emergence of stress‐adapted, profibrotic fibroblasts. Sustained shear exposure promotes the formation of stiff aggregates of mechanoadapative
Soyoun Min +6 more
wiley +1 more source
Visual stress and dyslexia for the practicing optometrist [PDF]
, 2016 Visual stress should not be confused with dyslexia. It refers to symptoms of discomfort and perceptual distortion that have a neurological origin. Pattern 2 of the Pattern Glare Test can be used to elicit symptoms of visual stress, but pattern 3 is of ...
Allen, Peter M +3 more
core
Advanced Science, EarlyView.The butterfly unfolded wing in an open form structure of botulinum neurotoxin type A (BoNT/A) at physiological‐state was confirmed at 2.85 Å resolution by cryo‐electron microscopy (cryo‐EM). Structure‐guided protein engineering significantly enhanced the receptor‐binding affinity, therapeutic efficacy, and safety of the engineered toxin variants ...
Wenrui Wang +16 more
wiley +1 more source
Review of simulating four classes of window materials for daylighting with non-standard BSDF using the simulation program Radiance [PDF]
, 2013 This review describes the currently available simulation models for window material to calculate daylighting with the program "Radiance". The review is based on four abstract and general classes of window materials, depending on their scattering and ...
Apian-Bennewitz, Peter
core
Depletion of the RNA‐Editing Enzyme ADAR1 Invigorates the Antitumor Immunity of NK Cells
Advanced Science, EarlyView.ADAR1 is upregulated in NK cells from melanoma patients, impairing their function. Its loss enhances NK cell tumor infiltration and cytotoxicity in vitro and in vivo. Mechanistically, ADAR1 deficiency destabilizes CD38 mRNA to reduce its expression, thereby increasing NK cell mobility and killing, which nominates it as a therapeutic target for NK cell ...
Shuhan Chen +11 more
wiley +1 more source
Susceptibility to pattern glare and the effect of spectral filters on rate of reading and visual search in stroke patients [PDF]
, 2013 The present thesis investigates pattern glare susceptibility following stroke and the immediate and prolonged impact of prescribing optimal spectral filters on reading speed, accuracy and visual search performance. Principal observations: A case report has shown that visual stress can occur following stroke.
openaire +1 more source
Advanced Science, EarlyView.This study developed a hierarchical targeting nanoplatform, siTREM2@ETP‐PEOz‐OMVs, against triple‐negative breast cancer (TNBC) bone metastasis. It precisely delivers therapeutic siTREM2 to monocytes/macrophages within the metastatic niche. This intervention dually regulates cell fate: reprogramming immunosuppressive macrophages and inhibiting ...
Fanglu Chen +12 more
wiley +1 more source