Results 131 to 140 of about 811,772 (320)

Methotrexate‐Loaded Liposomal Formulation Enables 6‐Week Sustained Intraocular Therapeutic Drug Release in a Porcine Model

Advanced Healthcare Materials, EarlyView.
A liposomal formulation for methotrexate enables minimally invasive, sustained intraocular drug delivery for over six weeks with a single injection. Developed for treating intraocular diseases like lymphoma and PVR, it offers excellent biocompatibility in vivo in a porcine model.
Maximilian Hammer, Lea Skrzypczyk, Sabrina Wohlfart, Bryan Calder Ackermann, Ludwig Geisweid, Simon William Pohl, Margarita Karaivanova, Jonathan Herth, Victor Aristide Augustin, Alexander Studier‐Fischer, Tina Sackmann, Leon Kaulen, Anna Steyer, Walter Mier, David H Steel, Kanmin Xue, Gerd Uwe Auffarth, Philipp Uhl   +17 more
wiley   +1 more source

An investigation into the use of CCTV footage to improve likeness in facial composites

, 2006
Facial composites are an important investigative tool and have been used in numerous high-profile cases (e.g. Yorkshire Ripper). Despite this, a great deal of research has indicated that composites often portray very poor facial resemblance to the ...
Bruce, Vicki, Ness, Hayley
core  

Natural Sweetener Stevioside‐Based Dissolving Microneedles Solubilize Minoxidil for the Treatment of Androgenic Alopecia

Advanced Healthcare Materials, EarlyView.
This study addresses limitations of minoxidil (MXD) in treating androgenetic alopecia by using stevioside (STV) as a solubilizing agent and microneedle (MN) material. STV enhanced MXD's solubility and skin absorption, leading to improved drug delivery and significant hair regrowth in animal models, demonstrating strong potential for AGA treatment ...
Junying Zhang, Tianyu Shao, Hailiang Li, Luying Zhu, Lamyaa Albakr, Nial J. Wheate, Lifeng Kang, Chungyong Wu   +7 more
wiley   +1 more source

Advances in Bioprinting to Model Immune‐Mediated Skin Diseases

Advanced Healthcare Materials, EarlyView.
This review explores how 3D bioprinting drives innovation in developing in vitro skin models that mimic immune‐mediated diseases. It highlights current technologies, key applications in studying skin pathologies, and emerging challenges. The review points toward future opportunities for improving disease modeling and advancing therapeutic and cosmetic ...
Andrea Ulloa‐Fernández, Marica Markovic, Julia Fernández‐Pérez, Georg Stary, Aleksandr Ovsianikov   +4 more
wiley   +1 more source

Enhancing therapeutic reasoning: key insights and recommendations for education in prescribing

BMC Medical Education
Background Despite efforts to improve undergraduate clinical pharmacology & therapeutics (CPT) education, prescribing errors are still made regularly. To improve CPT education and daily prescribing, it is crucial to understand how therapeutic reasoning ...
Mariëlle G. Hartjes, Milan C. Richir, Yoann Cazaubon, Erik M. Donker, Ellen van Leeuwen, Robert Likic, Yves-Marie Pers, Joost D. Piët, Fabrizio De Ponti, Walter Raasch, Floor van Rosse, Jitka Rychlícková, Emilio J. Sanz, Markus Schwaninger, Susanna M. Wallerstedt, Theo P. G. M. de Vries, Michiel A. van Agtmael, Jelle Tichelaar, On behalf of the EACPT Education Working group   +18 more
doaj   +1 more source

A Novel Approach to Personalized Personality Assessment with the Attachment-Caregiving Questionnaire: First Evidence in Favor of Interpretation-Oriented Inventory Designs

Psychology International
In clinical psychology and psychiatry, personality is usually assessed using questionnaires developed through factor analysis (FA). Essential domains are identified, which correspond to questions/items defining a (sub)scale, and each question is rigidly ...
Marcantonio Gagliardi, Marina Bonadeni, Sara Billai, Gian Luca Marcialis   +3 more
doaj   +1 more source

Distinguishing True From False Confessions Using Physiological Patterns of Concealed Information Recognition – A Proof of Concept Study Assistant Professor Honorary Research Fellow Associate Professor of Forensic Psychology

Wrongful conviction cases indicate that not all confessors are guilty. However, there is currently no validated method to assess the veracity of confessions. In this preregistered study, we evaluate whether a new application of the Concealed Information Test (CIT) is a potentially valid method to make a distinction between true and false admissions of ...
Linda Geven, Gershon Ben-Shakhar, Saul Kassin, Bruno verschuere   +3 more
openaire   +1 more source

Microneedle Technology in Psoriasis Management: Mechanistic Insights, Technological Innovation, Clinical Progress, and Challenges

Advanced Healthcare Materials, EarlyView.
This review explores the evolving role of microneedle systems in psoriasis management, highlighting their potential for enhanced drug delivery, diagnosis, and disease monitoring. It also discusses unmet clinical needs for psoriasis management and technical challenges, while outlining strategic directions to advance microneedle integration into routine ...
Fatma Moawad, Yasmine Ruel, Roxane Pouliot, Davide Brambilla   +3 more
wiley   +1 more source

Editorial: Deciphering population neuronal dynamics: from theories to experiments

Frontiers in Systems Neuroscience, 2023
Hongdian Yang, Woodrow L. Shew, Shan Yu, Artur Luczak, Carsen Stringer, Michael Okun   +5 more
doaj   +1 more source

Functional connectome gradient of prefrontal cortex as biomarkers of high risk for internet gaming disorder

NeuroImage
Adolescents and young adults are considered a high-risk group for internet gaming disorder (IGD). Early screening for high-risk individuals with IGD and exploring the underlying neural mechanisms is an effective strategy to reduce the harm of IGD.
Xinwen Wen, Lirong Yue, Zhe Du, Jiahao Zhao, Mengjiao Ge, Cunfeng Yuan, Hongmei Wang, Qinghua He, Kai Yuan   +8 more
doaj   +1 more source