Results 191 to 200 of about 51,701 (266)

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

FEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura, Kengo Furuichi, Hiromitsu Akamatsu, Naoki Yamamoto, Sako Keisuke, Akihiko Koshino, Taichiro Minami, Megumi Oshima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Kenta Takahashi, Minako Yamamura, Shin‐ichi Horike, Takiko Daikoku, Kenichi Harada, Yohei Shinmyo, Hiroshi Kawasaki, Takashi Wada, Yasunori Iwata   +19 more
wiley   +1 more source

System-level integration of halide perovskite optoelectronics for its commercial deployment. [PDF]

Nat Commun
Yang W, Yang X, Su R, Feng Y, Zhao L, Li M, Wang X, Zhu R, Pan C, Luo D.   +9 more
europepmc   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Opaque Social Instruments: A Cultural Evolutionary Approach to Pleistocene Symbolic Artifacts. [PDF]

Evol Anthropol
van Mazijk C.
europepmc   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Strategies to control cellular spatial organization in microphysiological systems. [PDF]

Microsyst Nanoeng
Truong HD, Ge Z, Chng E, Tran YV, Zhang Y, Lim CT.   +5 more
europepmc   +1 more source

amyloid-predict and LLPS-predict: Predicting phase separation propensities in the intrinsically disordered proteome. [PDF]

Proc Natl Acad Sci U S A
Lobo S, Griem L, Shell MS, Shea JE.
europepmc   +1 more source

Social and Anxiety-Like Behaviors Are Affected in Juvenile Mice With Gli2^+/- but Not Gli3^+/𝛥699 Genetic Modifications. [PDF]

Brain Behav
Niepsuj T, Nurani R, Carreras-Simons L, Bushman W, Jorgensen JS, Farhat WA, Auger AP.   +6 more
europepmc   +1 more source

Sticky interactions govern sequence-dependent dynamics in biomolecular condensates. [PDF]

Proc Natl Acad Sci U S A
Muthukumar K, Sundaravadivelu Devarajan D, Kim YC, Mittal J.   +3 more
europepmc   +1 more source

From Millimeters to Microns: A Hybrid Strategy for Reconfigurable Liquid-Crystal Patterning. [PDF]

Small Methods
Pradeep A, Montelongo Y, Ma JS, Xu Z, Wang T, Qin J, Nourshargh C, Booth MJ, Elston SJ, Morris SM.   +9 more
europepmc   +1 more source