Results 131 to 140 of about 723,635 (269)

Prometheus Revisited: From Liver to Heart. [PDF]

Liver Int
Riva MA.
europepmc   +1 more source

Adipocyte Myoglobin Is a Determinant of Energy Expenditure and a Potential Target to Limit Obesity

Advanced Science, EarlyView.
Myoglobin, known as a muscle oxygen‐carrying protein, is shown to play a key role in fat cells that burn energy. Loss of myoglobin reduces the body's ability to generate heat and increases obesity risk, while restoring it improves metabolism. The study identifies myoglobin as a regulator of fat burning and a potential target to enhance energy ...
Christian Strehlau, Helen Broghammer, Claudia Gebhardt, Anne Hoffmann, Tobias Hagemann, Şeyma Midilli, Rachel S. Zimmer, Kristin Schubert, Vasiliki Karagiannakou, Anastasia Georgiadi, Mario Ost, Martin Krüger, Lisa Roth, Kerstin Krause, Nora Klöting, Maria Keller, Martin Wabitsch, Rima Nuwayhid, Roland H. Stimson, Michael Stumvoll, Matthias Blüher, Juliane Weiner, John T. Heiker   +22 more
wiley   +1 more source

Correction: Watts et al. Multi-Antigen Elephant Endotheliotropic Herpesvirus (EEHV) mRNA Vaccine Induces Humoral and Cell-Mediated Responses in Mice. <i>Vaccines</i> 2024, <i>12</i>, 1429. [PDF]

Vaccines (Basel)
Watts JR, Clinton JLS, Pollet J, Peng R, Tan J, Ling PD.   +5 more
europepmc   +1 more source

Hyperpolarization of [1‐13C]Ketoisocaproate‐d2 by Reversible Exchange with Parahydrogen Enables Profiling of Branched‐Chain‐Amino‐Acid Metabolism in Cellulo and in Vivo

Advanced Science, EarlyView.
We report the fast generation of biocompatible solutions of highly 13C‐hyperpolarized (≈11%) partially‐deuterated ketoisocaproate within <6 min using spin‐lock‐induced crossing and reversible exchange with parahydrogen (SLIC‐SABRE). This enables rapid detection of branched‐chain‐amino‐acid transferase 1 (BCAT1) protein expression and investigation of ...
Stefan Petersen, Philipp R. Groß, Paul M. Schmidt, Henri de Maissin, Asitan Rittinger, Robert Willing, Adriana Sacristán‐Martín, Lisa Heß, Jule Koch, Sebastian Lucas, Maxim Zaitsev, Dominik von Elverfeldt, Martin Grashei, Franz Schilling, Jan‐Bernd Hövener, André F. Martins, Max von Delius, Thomas Reinheckel, Andreas B. Schmidt   +18 more
wiley   +1 more source

Beyond Painful Bones and Renal Stones: Acute Crystal Arthropathy of Dual Aetiology May Be an Unforeseen Complication Following Parathyroid Surgery. [PDF]

Cureus
Varghese AS, John R, Paul T, Jacob PM, Sigamani E, Cherian K.   +5 more
europepmc   +1 more source

Quality Thresholds for Angiogenesis Under Acoustic Manipulation in Engineered Vascular Tissues

Advanced Science, EarlyView.
Defined biological and physical quality thresholds achieved through acoustic manipulation regulate cellular alignment and spatial organization, promoting self‐assembling vasculature, extracellular matrix deposition, and angiogenic responses, thereby establishing critical acoustic patterning requirements for engineered vascular tissue development in ...
Oscar O'Dwyer Lancaster‐Jones, Russell Quinn, Niloofar Khoshdel Rad, Kilian Paul, Andrea Frank, Daniela F. Duarte Campos   +5 more
wiley   +1 more source

Direct Observation of Vortex Liquid Droplets in the Iron Pnictide Superconductor CaKFe4As4 at 0.5Tc

Advanced Science, EarlyView.
Vortex matter in the iron‐based superconductor CaKFe4As4${\rm CaKFe}_4{\rm As}_4$ is visualized at the nanoscale, revealing the unexpected emergence of vortex‐liquid droplets far below the critical temperature. These localized fluctuating regions coexist with a vortex solid, demonstrating that dissipation‐related dynamics arise well before macroscopic ...
Óscar Bou Marqués, Jose A. Moreno, Pablo García Talavera, Mingyu Xu, Juan Schmidt, Sergey L. Bud'ko, Paul C. Canfield, Isabel Guillamón, Edwin Herrera, Hermann Suderow   +9 more
wiley   +1 more source

Corrigendum to "Desacetyl-alpha-melanocyte stimulating hormone and alpha-melanocyte stimulating hormone are required to regulate energy balance" [Mol Metab 9 (2018) 207-216/29226825]. [PDF]

Mol Metab
Mountjoy KG, Caron A, Hubbard K, Shome A, Grey AC, Sun B, Bould S, Middlleditch M, Pontre B, McGregor A, Harris PWR, Kowalczky R, Brimble MA, Botha R, Tan KML, Piper SJ, Buchanan C, Lee S, Coll AP, Elmquist J.   +19 more
europepmc   +1 more source

Introducing Borsantrazole: A Trifunctional Boron‐Based Pyrazole That Extends the Lifespan of Amyotrophic Lateral Sclerosis Mice

Advanced Science, EarlyView.
Herein we report a boron‐based pyrazole, (Borsantrazole ‐ a small molecule that selectively targets oxidative stress) that significantly increases survival, reduces weight loss, delays disease onset, and affects global protein changes in the SOD1‐G37R mouse model of ALS.
Nitesh Sanghai, Rhonda Kelley, Ying Lao, M. Immanuel Reyes Madlangsakay, Prasanta Paul, M. Alejandra Llanes‐Cuesta, Jun‐Feng Wang, René P. Zahedi, Jiming Kong, Geoffrey K. Tranmer   +9 more
wiley   +1 more source

Conference Report-The Past, Current, and Future Challenges in Transplantation: A Festschrift in Honor of Professor Paul Anthony Keown. [PDF]

Can J Kidney Health Dis
Gill J, Stiller C, Lan J, Jevnikar A, Halloran PF, Rush D, Nickerson P, Cole E, Matas AJ, Formica R, Sawinski D, Blosser CD, Mannon RB, Keown PA.   +13 more
europepmc   +1 more source