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ED<sub>90</sub> of intravenous remimazolam for alleviating preoperative anxiety in children: a prospective dose-finding study. [PDF]
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Molecular Oral Microbiology, 2010Summary The pneumococcal cell surface protein PavA is a virulence factor associated with adherence and invasion in vitro. In this study we show in vivo that PavA is necessary for Streptococcus pneumoniae D39 colonization of the murine upper respiratory tract in a long-term carriage model, with PavA-deficient pneumococci being quickly cleared from ...
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ICSA Book Series in Statistics, 2017The isotonic regression solves many order restricted maximum likelihood estimation problems. This method, especially with the combination of the celebrated EM algorithm, is a powerful mathematical tool to tackle many important and difficult statistical problems. In this chapter we give a few examples to illustrate this method.
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