Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
EVALUATION PAVEMENT DISTRESSES USING PAVEMENT CONDITION INDEX [PDF]
, 2011 Pavement deterioration is resulted by both environmental and structural causes. It is difficult to maintain the road on the same specification that was owned at the opening and problems start to appear represented in the pavement cracks, holes and ...
kushardjoko, wahyudi +2 more
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Effectiveness of Glass Fiber Mesh Reinforcement Applied to Road Construction Located in a Mining Subsidence Area [PDF]
, 2019 Local district roads represent low technological regime when it comes to rehabilitation treatments. Analysed road is located in a mining subsidence area in Upper Silesia in Poland.
Kałuźa, Mateusz, Kotasiński, Miroslaw
core +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Determining the relationship between rock colour and the type of physical weathering on desert pavements in arid landscapes, Ras Al Khaimah, UAE [PDF]
, 2008 Despite opposition to the theory that diurnal heat fluxes within desert rocks cause enough internal stress to form cracks on clasts leading to the break down of the desert material, this study provides further evidence that this is a credible process in ...
O.J.H. Swift
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Detection of curved lines with B-COSFIRE filters: A case study on crack delineation
, 2017 The detection of curvilinear structures is an important step for various computer vision applications, ranging from medical image analysis for segmentation of blood vessels, to remote sensing for the identification of roads and rivers, and to biometrics ...
A Hoover +20 more
core +1 more source
An analytical and experimental assessment of flexible road ironwork support structures [PDF]
, 2003 This paper describes work undertaken to investigate the mechanical performance of road ironwork installations in highways, concentrating on the chamber construction.
A.C. Collop +11 more
core +2 more sources
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
Intelligent identification of pavement cracks based on PSA-Net
Frontiers in Environmental Science, 2023 The identification of pavement cracks is critical for ensuring road safety. Currently, manual crack detection is quite time-consuming. To address this issue, automated pavement crack-detecting technology is required.
Xuan Lin +6 more
doaj +1 more source
Performance of TenCate Paving Interlayers in Asphalt Concrete Pavements [PDF]
, 2017 As a continued effort of a previously completed project entitled “Performance of TenCate Mirafi PGM-G4 Interlayer-Reinforced Asphalt Pavements in Alaska,” this project evaluated two newly modified paving interlayers (TruPave and Mirapave) through overlay,
Li, Lin, Liu, Jenny, Zhao, Sheng
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