Results 41 to 50 of about 1,792 (255)

LRG1 Drives Pathological Angiogenesis by Disrupting Neutrophil Mitochondrial Homeostasis in Bladder Cancer

open access: yesAdvanced Science, EarlyView.
In bladder cancer, LRG1 binds to ANXA2 to trigger mitochondrial ROS‐dependent NETosis. This pathogenic cascade actively uncouples endothelial‐mural cell interactions, driving profound vascular destabilization. Consequently, targeting the LRG1‐ANXA2 axis attenuates the neutrophil burden and induces structural vascular normalization, offering a powerful ...
Dongshan Chen   +8 more
wiley   +1 more source

ASSESSMENT OF HIGHWAY PAVEMENT DISTRESSES SUBJECTED TO OVERLOADING IN HILLA CITY: A ROAD NO. 80 CASE STUDY

open access: yesMağallaẗ Al-kūfaẗ Al-handasiyyaẗ
Roadway pavements constitute a vital component of transportation infrastructure, and their effective maintenance and rehabilitation are paramount to ensure optimal functionality.
Alia jasem, Hayder Abbas
doaj   +1 more source

AI‐Assisted IoT‐Enabled ECG Monitoring: Integrating Foundational and Generative AI Tools for Sustainable Smart Healthcare—Recent Trends

open access: yesAI &Innovation, EarlyView.
ABSTRACT The rapid evolution of the Internet of Things (IoT) has significantly advanced the field of electrocardiogram (ECG) monitoring, enabling real‐time, remote, and patient‐centric cardiac care. This paper presents a comprehensive survey of AI assisted IoT‐based ECG monitoring systems, focusing on the integration of emerging technologies such as ...
Amrita Choudhury   +2 more
wiley   +1 more source

Towards Low-Cost Pavement Condition Health Monitoring and Analysis Using Deep Learning

open access: yesApplied Sciences, 2020
Governments are faced with countless challenges to maintain conditions of road networks. This is due to financial and physical resource deficiencies of road authorities. Therefore, low-cost automated systems are sought after to alleviate these issues and
Ronald Roberts   +3 more
doaj   +1 more source

Beyond the label: Rethinking off‐label drug use in paediatrics. Towards a scientifically grounded and safer future for paediatric pharmacotherapy

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Despite regulatory progress being made in the past two decades, off‐label drug use in paediatrics remains pervasive, with prevalence estimated between 3% and 97% of prescriptions across different clinical settings. Off‐label use—defined as prescribing outside the conditions described in the Summary of Product Characteristics (SmPC)—is often ...
Tjitske M. van der Zanden   +3 more
wiley   +1 more source

Development of Korea Airport Pavement Condition Index for Panel Rating

open access: yesApplied Sciences, 2022
Airports strive to prevent safety issues, such as foreign object debris (FOD), by pavement management using the pavement condition index (PCI). The index is used in decision-making processes for overall pavement maintenance and repair, such as the ...
Nam-Hyun Cho   +3 more
doaj   +1 more source

Exploring new avenues: Psychedelic‐assisted therapy for young people

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Rates of mental illness in young people are increasing, whereas the development of novel mental health treatments has not significantly progressed. Psychedelic‐assisted therapy, using substances such as psilocybin and 3,4‐methylenedioxymethamphetamine (MDMA), has shown potential in the treatment of mental illnesses in the adult population, including ...
Ioanna Artemis Vamvakopoulou   +3 more
wiley   +1 more source

How Do Global Fashion Supply Chains Respond to Structural Pressures? Examining Sustainability Conduct Through a Spatial–Temporal–Functional Lens

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT The fashion industry is facing unprecedented structural pressures, including increasing regulatory demands and rising expectations for social accountability. This study examines how global fashion supply chains respond to such pressures to advance sustainability.
Diletta Tosetto   +2 more
wiley   +1 more source

Second-Order Statistical Texture Representation of Asphalt Pavement Distress Images Based on Local Binary Pattern in Spatial and Wavelet Domain [PDF]

open access: yesJournal of Rehabilitation in Civil Engineering, 2019
Assessment of pavement distresses is one of the important parts of pavement management systems to adopt the most effective road maintenance strategy. In the last decade, extensive studies have been done to develop automated systems for pavement distress ...
Reza Shahabian Moghaddam   +3 more
doaj   +1 more source

Strategic Shift to Sustainable Competitive Advantage With Biodiversity Purpose: An Adaptive Capacity Approach

open access: yesCorporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT Drawing on adaptive capacity research, this study provides an assessment of the sustainable competitive advantage of a strategic shift with social purpose, leveraging green revenue to drive biodiversity outcomes. The study employs panel regression analysis on a distinctive dataset for the period 2015–2024, focusing on S&P 1500 firms. Using the
Post Raj Pokharel   +1 more
wiley   +1 more source

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