Results 71 to 80 of about 2,463 (283)

HDM-4 Deterioration Modelling: Validation and Adoption for Flexible Pavements With Modified Bituminous Road Surfacing

open access: yesThe Baltic Journal of Road and Bridge Engineering, 2019
Highway Development and Management (HDM-4) is an internationally recognised tool to analyse pavement management and investment alternatives. The HDM-4 pavement deterioration models help to predict the initiation and progression of various pavement ...
Sanjay Deori   +3 more
doaj   +1 more source

Chemotherapy‐Induced Nausea and Vomiting in Early Breast Cancer Patients Receiving Adjuvant Chemotherapy With Fluorouracil, Epirubicin, Cyclophosphamide Followed by Docetaxel Versus an Anthracycline‐Free Regimen With Docetaxel, Cyclophosphamide—Results From a Randomized Clinical Trial

open access: yesInternational Journal of Cancer, EarlyView.
Chemotherapy‐induced nausea and vomiting (CINV) remains a significant clinical problem despite modern antiemetics. In particular, antiemetic strategies for emerging cancer therapies lack detailed evaluation. This randomized trial analyzed hourly CINV data for patients with early breast cancer who received either docetaxel plus cyclophosphamide (TC) or ...
Manuel Hörner   +16 more
wiley   +1 more source

A multiplex interactome of Ebola virus proteins reveals TM9SF2 as a cell‐surface attachment factor that promotes viral entry

open access: yesiMetaOmics, EarlyView.
This study generates a comprehensive Ebola virus (EBOV)‐human protein–protein interactome, comprising 1728 core high‐confidence interactions. Further interactome analysis revealed the potential association of EBOV glycoprotein (GP) with the host factor TM9SF2. Subsequent mechanistic investigations confirmed that TM9SF2 functions as an attachment factor
Limin Shang   +16 more
wiley   +1 more source

Sampietrini Stone Pavements: Distress Analysis Using Pavement Condition Index Method [PDF]

open access: yesApplied Sciences, 2017
In several Italian cities, it is possible to find historical pavements such as the Sampietrini pavements, which are mainly located in the center of the city of Rome. The Sampietrini pavement is a particular road surface paved in natural stone with irregular sharp elements that are assembled by hand with the evident not plan effect.
ZOCCALI, PABLO   +2 more
openaire   +1 more source

Analysis of Distresses in Asphalt Pavement Transitions on Bridge Approaches and Departures [PDF]

open access: yes, 2017
Some highway agencies in the United States are experiencing frequent distresses in asphalt pavements on bridge approaches/departures. Commonly observed distresses include alligator cracking and rutting, which reduce roadway smoothness and safety.
Rajalingola, Manvitha
core   +1 more source

Pavement Distresses Due to Truck Platoons: A Holistic Analysis [PDF]

open access: yes
69A3551747105Currently, AASHTOWare PMED does not contain a framework to compute distresses for loading scenarios like truck platoons. Truck platoons reduce fuel consumption and improve safety while increasing pavement damage because of a reduction in ...
Ozer, Hasan   +5 more
core   +1 more source

Complement C3 mediates adolescent social isolation‐induced hippocampal synaptic deficits and sex‐specific emotional dysfunction

open access: yesInterdisciplinary Medicine, EarlyView.
Adolescent social isolation disrupts hippocampal function and exacerbates emotional symptoms, with sex‐specific patterns, as shown by human studies. In mice, social isolation decreased hippocampal synaptic density and calcium signaling, upregulated complement proteins, and activated complement‐mediated microglial synaptic phagocytosis.
Yuwan Qi   +13 more
wiley   +1 more source

Alterations in MicroRNA and Cytokine Expressions in Placental and Amniotic Tissues of COVID‐19 Affected Pregnant Women

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Since 2019, coronavirus disease 2019 (COVID‐19) has been associated with increased risks of preterm birth and placental complications. We prospectively investigated alterations in microRNAs (miRNAs) and cytokines in placental and amniotic tissues from pregnant women with and without COVID‐19 to evaluate the infection's impact on pregnancy ...
Wei‐Chun Chen   +3 more
wiley   +1 more source

Short term performance and effect of speed humps on pavement condition of Alexandria Governorate roads

open access: yesAlexandria Engineering Journal, 2014
The road network in Alexandria Governorate includes approximately 3800 km of roads. In the recent years, it was observed that some of these roads failed prematurely within 3–5 years of construction.
Wael Bekheet
doaj   +1 more source

Portland Cement Concrete Pavement Thickness And Shear Wave Velocity Variation Versus Observed Pavement Distresses [PDF]

open access: yes, 2017
University of Minnesota M.S. thesis. February 2017. Major: Geological Engineering. Advisors: Randal Barnes, Lev Khazanovich. 1 computer file (PDF); ii, 135 pages.Concrete slab thickness is the key design characteristic of a concrete pavement.
Conway, Ryan
core  

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