Results 51 to 60 of about 18,351 (301)
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Preparing for the Next Transformation in Pavement Management [PDF]
, 2015 Since the initial development of a systems approach for managing pavements in the late 1970's and early 1980's, there have been tremendous changes in the way transportation agencies have designed, constructed, and managed their pavement networks. In just
Zimmerman, Kathryn A.
core
Mapping the spatial variation of soil moisture at the large scale using GPR for pavement applications [PDF]
, 2015 The characterization of shallow soil moisture spatial variability at the large scale is a crucial issue in many research studies and fields of application ranging from agriculture and geology to civil and environmental engineering.
M. Giudici +9 more
core +1 more source
Astrocyte heterogeneity in brain metastases
Molecular Oncology, EarlyView.Astrocytes emerge as pivotal regulators of metastatic colonization, survival, immune remodeling, and therapy response associated with an increasing heterogeneity that requires spatially and longitudinally resolved approaches to uncover regulatory programs and guide context‐specific therapies.
Carolina Hernández‐Oliver +2 more
wiley +1 more source
Pavement Markings and Safety Final Report, November 2010 [PDF]
, 2010 Previous research on pavement markings from a safety perspective tackled various issues such as pavement marking retroreflectivity variability, relationship between pavement marking retroreflectivity and driver visibility, or pavement marking ...
core
Non-Newtonian Behaviors of Crumb Rubber-Modified Bituminous Binders
Applied Sciences, 2018 Crumb rubber-modified bitumen (CRMB) has been utilized in the asphalt paving industry for decades due to its various benefits. The complex interaction between bitumen and crumb rubber as well as the addition of warm-mix additives makes the typical laws ...
Haopeng Wang +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
wiley +1 more source
Safety Impacts of Pavement Edge Drop-offs, 2006 [PDF]
, 2006 A vehicle may leave its travel lane for a number of reasons, such as driver error, poor surface conditions, or avoidance of a collision with another vehicle in the travel lane.
core
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
Durable, Cost-Effective Pavement Markings Phase I: Synthesis of Current Reseaech; TR-454, June 2001 [PDF]
, 2001 Pavement marking technology is a continually evolving subject. There are numerous types of materials used in the field today, including (but not limited to) paint, epoxy, tape, and thermoplastic.
core