Results 31 to 40 of about 8,823,551 (213)

Assessing reinforced pavement performance: Influence of geogrid position, axial stiffness, and applied stress

CTU Journal of Innovation and Sustainable Development
This study examined the performance of pavement, considering geogrid’s position within the pavement layers, geogrid’s axial stiffness, and applied stress through the Plaxis 2D program.
Tan-Hung Nguyen, Kyra Kamille A. Toledo, Trong Phuoc Huynh   +2 more
doaj   +3 more sources

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

MEPDG Work Plan Task No. 7: Existing Pavement Input Information for the Mechanistic-Empirical Pavement Design Guide, 2009 [PDF]

, 2009
The objective of this study is to systematically evaluate the Iowa Department of Transportation’s (DOT’s) existing Pavement Management Information System (PMIS) with respect to the input information required for Mechanistic-Empirical Pavement Design ...

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KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

A state-of-the-art assessment in developing advanced concrete materials for airport pavements with improved performance and durability

Case Studies in Construction Materials
Concrete materials, as the main component of airport pavement, provide essential attributes such as strength and toughness required by airport pavement.
Minghou Li, Wei Zhang, Fengjuan Wang, Yingshuo Li, Zhiyong Liu, Qingyu Meng, Fei Huo, Duo Zhao, Jinyang Jiang, Jiawen Zhang   +9 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Review of road pavement performance in various countries [PDF]

Дороги і мости
Introduction. High quality and durable highway pavements are one of the preconditions for the efficient road traffic in every country. Problem Statement. The high-level and scientifical design, construction, maintenance, and rehabilitation of pavement
Altin Seranaj, Diana Bardhi, László Gáspár, Zsolt Bencze   +3 more
doaj   +1 more source

Predicting Rutting Development of Pavement with Flexible Overlay Using Artificial Neural Network

Applied Sciences, 2023
Pavement maintenance and repair is a crucial part of pavement management systems. Accurate and reliable pavement performance prediction is the prerequisite for making reasonable maintenance decisions and selecting suitable repair schemes.
Chunru Cheng, Chen Ye, Hailu Yang, Linbing Wang   +3 more
doaj   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source