Results 51 to 60 of about 9,028,773 (310)

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

GBS‐MeDIP: A method for the simultaneous identification of genetic and epigenetic variants in tumors

FEBS Open Bio, EarlyView.
GBS‐MeDIP combines DNA sequencing with enrichment of methylated DNA to profile genetic and epigenetic variation in the same reduced genomic fraction. Applied to gastric cancer and parathyroid tumors, it identifies sequence variants, copy number changes, and differentially methylated regions together, helping distinguish true epigenetic changes from ...
Fábio Pértille, Shiva Rezaei, Julia Uffenorde, Oliver Gimm, Mohammad Ali Hosseinpour Feizi, Luiz Lehmann Coutinho, Carlos Guerrero‐Bosagna   +6 more
wiley   +1 more source

Review of road pavement performance in various countries [PDF]

Дороги і мости
Introduction. High quality and durable highway pavements are one of the preconditions for the efficient road traffic in every country. Problem Statement. The high-level and scientifical design, construction, maintenance, and rehabilitation of pavement
Altin Seranaj, Diana Bardhi, László Gáspár, Zsolt Bencze   +3 more
doaj   +1 more source

Predicting Rutting Development of Pavement with Flexible Overlay Using Artificial Neural Network

Applied Sciences, 2023
Pavement maintenance and repair is a crucial part of pavement management systems. Accurate and reliable pavement performance prediction is the prerequisite for making reasonable maintenance decisions and selecting suitable repair schemes.
Chunru Cheng, Chen Ye, Hailu Yang, Linbing Wang   +3 more
doaj   +1 more source

Surface modification of 3D‐printed polycaprolactone scaffolds with silk fibroin for bone tissue engineering

FEBS Open Bio, EarlyView.
Coating 3D‐printed PCL scaffolds with silk fibroin can improve biocompatibility and bone cell adhesion. One innovative design for tissue‐engineering scaffolds uses 3D printing technology. Here, we used polycaprolactone (PCL) filament as a biocompatible material to design a porous 3D scaffold for bone tissue engineering.
Hamed Koeini, Esmaeil Biazar, Davood Zaeifi, Reza Zeinali, Saeed Heidari‐Keshel, Amimasoud Hassanour, Helia Saheli, Arezou Mehrabi   +7 more
wiley   +1 more source

Study on Skid Resistance of Asphalt Pavements Under Macroscopic and Microscopic Texture Features: A Review of the State of the Art

Applied Sciences
Pavement skid resistance is one of the most important factors affecting road safety, and pavement texture morphology significantly influences this property.
Wei Chen, Zhengchao Zhang, Jincheng Wei, Xiaomeng Zhang, Wenjuan Wu, Yuxuan Sun, Guangyong Wang   +6 more
doaj   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Study on the performance of environmental micro-surfacing for exhaust purification

Materials Research Express, 2022
In order to endow pavement materials with environmental protection properties such as automobile exhaust purification, an environmentally friendly micro-surfacing material with exhaust purification was prepared.
Zhenxia Li, Tengteng Guo, Yuanzhao Chen, Mingzhu Yang, Ning Wang, Jing Wang, Lihui Jin   +6 more
doaj   +1 more source

Performance improvement model of cement pavement in seasonal-frost regions

Magazine of Civil Engineering, 2022
To effectively evaluate the performance improvement of cement pavement in seasonal frost regions, the typical diseases of cement concrete pavements in seasonal frost regions are proposed through the analysis of measured data, and the influence factors of
Zhao Qianqian, Fu Qiang, Zhang Hetong, Wang Jianwu   +3 more
doaj   +1 more source

Global Rather Than Vertical‐Selective Saccadic Abnormalities in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To test whether vertical saccades are preferentially affected in Progressive Supranuclear Palsy (PSP). Methods PSP patients (n = 24) were compared to age‐matched controls (n = 94) and two degenerative groups (Alzheimer's disease, n = 20; Lewy body disease, n = 50).
Duy Duan Nguyen, Mark Paine, Soohyun Lee, Amir Fazlollahi, Baibin (Ben) Wang, John D. O'Sullivan, Peter J. Nestor   +6 more
wiley   +1 more source