Results 191 to 200 of about 19,447 (222)
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Pax3 and Pax7 expression and regulation in the avian embryo
Anatomy and Embryology, 2006Satellite cells are essential for postnatal growth and repair of skeletal muscle. The paired-box transcription factors Pax3 and Pax7 are expressed in emerging muscle precursors. Recent studies have traced the origin of satellite cells to the embryonic dermomyotome, however, their developmental regulation throughout embryogenesis remains unclear.
Anthony, Otto +2 more
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Characterization of the alternate allelic forms of human PAX7
Mammalian Genome, 2000Six different allelic forms of the human neurogenic and myogenic developmental gene, PAX7, have been identified. They are distinguished by the number of tandem tetranucleotide, GAAG, repeats at a polymorphic site within the second intron of the paired box.
Ziman, M.R. +3 more
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The Role of Pax3 and Pax7 in Development and Cancer
Critical Reviews™ in Oncogenesis, 1998Pax genes consist of a family of transcription factors that are essentially required for the genesis of a variety of tissues and organs. Pax3 and Pax7 are specifically expressed in the dorsal neural tube and the developing somite. Loss-of-function mutations of Pax3 in Splotch mice and in Waardenburg syndrome in man revealed that Pax3 is necessary for ...
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Generation of a Rat Monoclonal Antibody Specific for Pax7
Hybridoma, 2009Pax7 is a nuclear localization protein, well known as a member of the paired box family. It is expressed at a very early stage of muscle differentiation and is also found in muscle satellite cells that are recognized as muscle stem cells. Pax7 is also recognized as a tumor cell marker since it is greatly expressed in various types of tumor cells.
Akihito, Harada +5 more
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The role of Pax7 in determining the cytoarchitecture of the superior colliculus
Development, Growth & Differentiation, 2004Pax genes are a family of transcriptional regulators vital for embryonic development. One member of the family, Pax7, functions early in neural development to establish dorsal polarity of the neural tube, and continuous refinement of its expression affords regional identity to brain nuclei, in particular the superior colliculus. Pax7 expression within
Jennifer, Thompson +2 more
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Cyclin D3 promotes myogenic differentiation and Pax7 transcription
Journal of Cellular Biochemistry, 2011AbstractDifferentiation of skeletal muscle myoblasts involves activation of muscle‐specific markers such as MyoD, Myf5, MRF4, and myogenin, followed by exit from the cell cycle, expression of structural proteins, and fusion into multinucleated myotubes. Cyclin D3 is upregulated during muscle differentiation, and expression of cyclin D3 in proliferating
Ritika, Gurung, Veena K, Parnaik
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Pax3 functions in cell survival and in pax7 regulation
Development, 1999Abstract In developing vertebrate embryos, Pax3 is expressed in the neural tube and in the paraxial mesoderm that gives rise to skeletal muscles. Pax3 mutants develop muscular and neural tube defects; furthermore, Pax3 is essential for the proper activation of the myogenic determination factor gene, MyoD, during early muscle development ...
A G, Borycki +4 more
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2014
Muscle satellite cells (i.e., muscle stem cells) are mainly responsible for postnatal muscle growth and regeneration. Pax7, a transcription factor of the paired-domain-containing proteins, is preferentially expressed in the quiescent muscle satellite cell and proliferating myoblast.
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Muscle satellite cells (i.e., muscle stem cells) are mainly responsible for postnatal muscle growth and regeneration. Pax7, a transcription factor of the paired-domain-containing proteins, is preferentially expressed in the quiescent muscle satellite cell and proliferating myoblast.
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Comparison of the proximal promoter regions of the PAX3 and PAX7 genes
Cancer Genetics and Cytogenetics, 2007Translocations t(2;13)(q35;q14) and t(1;13)(p36;q14), which fuse PAX3 and PAX7, respectively, to FOXO1A, characterize alveolar rhabdomyosarcoma. Previous studies have suggested that the expression of PAX7-FOXO1A is copy-number dependent, but that of PAX3-FOXO1A is not, which may be due to a weaker PAX7 than PAX3 promoter.
Emely, Möller +4 more
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Biphenotypic Sinonasal Sarcoma with PAX7 Expression
International Journal of Surgical Pathology, 2022Natalia Georgantzoglou +4 more
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