Entropy‐Driven Physical Amplification in Multivalent Biosensing
Detecting scarce molecules usually demands enzymatic amplification such as PCR. A statistical‐mechanical theory now reveals a purely physical alternative: distributing a fixed binding strength over more linker arms exponentially lowers the concentration at which multivalent sensors switch on.
Yuhan Peng, Xiuyang Xia, Ran Ni
wiley +1 more source
How Organizations Sustain the National Diabetes Prevention Program: Real-world Strategies for Financing and Cost Control. [PDF]
Ritchie ND, Turk M.
europepmc +1 more source
From Sensing Mechanisms to System Co‐Design: Graphene‐Based Sensors and Readout Circuits
This review establishes a unified PS–EQ–RF framework linking graphene sensing mechanisms, native electrical outputs, and output‐specific readout circuits. Voltage‐, current‐, resistance‐, and capacitance‐type sensing systems are systematically classified to guide architecture selection, low‐noise design, system co‐design, and practical integration ...
Jinduo Zhang +5 more
wiley +1 more source
Leading Career and Programmatic Development: Short-term Implementation, Planning, and Organization While Pursuing a Long-term Growth and Culture Mindset. [PDF]
Waters PM +3 more
europepmc +1 more source
An enzyme–nitric oxide (NO) co‐regulatory strategy reprograms pathological extracellular matrix (ECM)–fibroblast crosstalk in hypertrophic scars. Enzymatic degradation of pre‐existing ECM relieves aberrant mechanical cues, while NO‐mediated fibroblast phenotypic modulation restrains excessive collagen synthesis.
Junzhe Fu +7 more
wiley +1 more source
A qualitative study of stakeholders' perceptions towards the implementation of the National Health Insurance Scheme in Zambia: equity and financial sustainability in question. [PDF]
Kazibwe J +7 more
europepmc +1 more source
TUBA1B is consistently upregulated in hepatocellular carcinoma and sustains malignant progression by stabilizing G3BP2. By restraining TRIM25‐associated K48‐linked ubiquitination, TUBA1B preserves the G3BP2–IκBα complex and basal NF‐κB/p65 activity. Concurrent TUBA1B/G3BP2 upregulation identifies an aggressive HCC subgroup with enhanced p65 activation ...
Fen Lin +10 more
wiley +1 more source
Public perceptions and willingness-to-pay regarding over-the-counter (OTC) naloxone: A national cross-sectional survey informed by the Theory of Planned Behavior. [PDF]
Randles A +12 more
europepmc +1 more source
Self‐compensation effects attributed to doping‐dependent shift‐defects at APBs Validation of Hall data for VRH transport near the MIT Persistence of VRH transport for any SiH4 flow in Si‐doped κ‐Ga2O3 due to high compensation coupling transport and EPR data as strategy to study electronic properties and doping T‐dependence of transport data agrees with
Antonella Parisini +9 more
wiley +1 more source
Developing a patient reported measure on out-of-pocket healthcare expenditure among Aboriginal patients: a formative study. [PDF]
Ryder C +18 more
europepmc +1 more source

