Results 251 to 260 of about 252,491 (337)

Dead Matter, Living Machines: Repurposing Crustaceans' Abdomen Exoskeleton for Bio‐Hybrid Robots

Advanced Science, EarlyView.
Crustacean exoskeletons, repurposed from food waste, are engineered into sustainable bending actuators combining biotic structure with synthetic control. The augmented exoskeletons achieve rapid and robust motion with lightweight body and can be used as part of robotic manipulators, grippers and swimmers.
Sareum Kim, Kieran Gilday, Josie Hughes
wiley   +1 more source

The evolving landscape of antibody-drug conjugates (ADCs) for treatment of prostate cancer. [PDF]

NPJ Precis Oncol
Lin C, Hadfield MJ, Santopietro A, Lagos G, Cheng L, El-Deiry WS, Aggarwal R, Mega A, Hyams E, Carneiro BA.   +9 more
europepmc   +1 more source

Online Payload Identification for Quadruped Robots

, 2017
Guido Tournois, Michele Focchi, Andrea Del Prete, Romeo Orsolino, Darwin G. Caldwell, Claudio Semini   +5 more
openalex   +1 more source

Development of Dimethylsulfonium Probes for Broad Profiling of Methyllysine Reader Proteins

Advanced Science, EarlyView.
Development of oligoglycine‐based dimethylsulfonium probes for unbiased crosslinking to methyllysine readers. The general probe facilitates profiling of site‐specific methyllysine readers, evaluation of selectivity and activity of reader inhibitors, and global profiling of methyllysine readers.
Jinyu Yang, Yihang Xiao, Yingxiao Gao, Mingxuan Wu   +3 more
wiley   +1 more source

Supplementary Figure 4 from Anti-HER2, High-DAR Antibody Fragment–Drug Conjugates with a Glucuronide-Based MMAE Linker–Payload Demonstrate Superior Efficacy over IgG-Based ADCs [PDF]

Ioanna Stamati, Gökhan Yahioglu, Soraya Diez-Posada, Anja Pomowski, Isabel Perez-Castro, A. Keith Stewart, Laura Bouché, Antony Constantinou, Benjamin J. Stenton, Savvas Saouros, Bryan Edwards, Sam Ness, Mahendra P. Deonarain   +12 more
openalex   +1 more source

Oncolytic Probiotics with Molecular Pili for Solid Tumor Therapy

Advanced Science, EarlyView.
This study identifies Lactobacillus rhamnosus as an intrinsic oncolytic agent that triggers tumor metabolic collapse via calcium‐dependent ROS bursts. By chemically anchoring collagen‐targeting “molecular pili” to the bacterial surface, the engineered non‐transgenic probiotic (LR@MP) achieves targeted colonization and potent solid tumor suppression ...
Haodong Ge, Chengsheng Ding, Xiao Yang, Si Gao, Changjie Yang, Yuchen Hou, Hongye Wang, Linke Bian, Hao Zhong, Yifan Qu, Luyang Zhang, Junjun Ma, Zhengwei Cai, Wenguo Cui, Minhua Zheng   +14 more
wiley   +1 more source

Expanding the payload scope in antibody-drug conjugates by delivery of hydroxy-containing drugs through self-immolative phosphoramidates. [PDF]

Nat Commun
Ochtrop P, Jagtap AP, Felber JG, Vogt S, Herterich S, Mai I, Cyprys P, Schmitt S, Payer S, Kitowski A, Wunder S, Machui P, Brandmeier J, Leonardi N, Poliak E, Hackenberger CPR, Marcq O, Schumacher D, Helma J, Vogl AM, Kasper MA.   +20 more
europepmc   +1 more source

ADEPT for Secondary Payloads

, 2014
Brandon Smith, Alan M. Cassell, Ethiraj Venkatapathy   +2 more
openalex   +1 more source

Supplementary Figure S1 from Design and Evaluation of ZD06519, a Novel Camptothecin Payload for Antibody Drug Conjugates

Mark E. Petersen, Michael G. Brant, Manuel Lasalle, Samir Das, Renee Duan, Jodi Wong, Tong Ding, Kaylee J. Wu, Dayananda Siddappa, Chen Fang, Wen Zhang, Alex M. L. Wu, Truman Hirkala-Schaefer, Graham A. E. Garnett, Vincent Fung, Luying Yang, Andrea Hernández Rojas, Samuel O. Lawn, Stuart D. Barnscher, Jamie R. Rich, Raffaele Colombo   +20 more
openalex   +1 more source

Advanced polymer nanocapsules with enhanced capabilities for controlled-release of payloads

, 2016
Shahed Behzadi
openalex   +2 more sources