Results 271 to 280 of about 1,938,290 (341)

CLAE: A High‐Fidelity Nanopore Sequencing Strategy for Read‐Level Viral Variant Detection and Environmental RNA Virus Discovery

open access: yesAdvanced Science, EarlyView.
High‐fidelity Nanopore sequencing offers a cost‐effective, portable path to uncovering viral dark matter in complex environments—but suffers from severe read‐length bias, low throughput, and limited accuracy. This study traces these limitations to core biochemical barriers and introduces CLAE, a foundational high‐fidelity platform that enables accurate,
Hannah Yu   +14 more
wiley   +1 more source

Mitochondrial Transplantation Augments the Reparative Capacity of Macrophages Following Myocardial Injury

open access: yesAdvanced Science, EarlyView.
Mitochondrial transplantation induces macrophage polarization toward an anti‐inflammatory M2 phenotype, enhances their reparative capacities, and facilitates mitochondrial transfer to cardiomyocytes, collectively promoting tissue repair and functional recovery post‐myocardial infarction.
Yuning Zhang   +10 more
wiley   +1 more source

Big Data and AI‐Powered Modeling: A Pathway to Sustainable Precision Animal Nutrition

open access: yesAdvanced Science, EarlyView.
This review summarizes the current landscape of big data and AI‐powered modeling in animal nutrition, covering techniques including intelligent data acquisition, data augmentation, explainable machine learning, heuristic algorithms, and life cycle assessment‐based sustainability evaluation.
Shuai Zhang   +3 more
wiley   +1 more source

Tumor Intrinsic METTL5 Modulates ATF4 Translation to Prevent T Cell‐Induced Ferroptosis in Ovarian Cancer

open access: yesAdvanced Science, EarlyView.
An integrative analysis combining in vitro genome‐wide immune screens, in vivo ICB screens, and clinical data mining identifies METTL5 as a key tumor‐intrinsic immune factor. Mechanistic studies further reveal the importance of the METTL5‐ATF4‐SLC7A11/SLC3A2‐ferroptosis axis in modulating antitumor immune responses. These findings highlight METTL5 as a
Jiakai Hou   +30 more
wiley   +1 more source

Facet‐dependent Heterogeneous Fenton Reaction Mechanisms on Hematite Nanoparticles for (Photo)catalytic Degradation of Organic Dyes

open access: yesAdvanced Science, EarlyView.
This study reveals how hematite crystal facets govern heterogeneous (photo)‐Fenton degradation of organic dyes. Facet‐dependent differences in H2O2 decomposition and reactive oxygen species generation are demonstrated, providing mechanistic insights that inform environmental strategies for water purification and pollutant remediation. Abstract Although
Ping Chen   +15 more
wiley   +1 more source

Ultrahigh Seebeck Coefficient and Power Factor in Low‐Temperature Fused Ag2Se Films via Superionic‐Driven Plastic Deformation

open access: yesAdvanced Science, EarlyView.
Driven by superionic‐induced plastic deformation, low‐temperature treatment can not only effectively fuse Ag2Se nanoparticles into a dense film but also enhance thermoelectric performance by maximally preserving effective grain boundaries resulting in intensive energy filtering effect. Notably, excess Ag nanoclusters act as fusing agents, promoting the
Dezhuang Ji   +7 more
wiley   +1 more source

Graphitized Biochar Derived from Agricultural Wastes Enhances Methanogenesis via Conductivity‐Driven Direct Interspecies Electron Transfer

open access: yesAdvanced Science, EarlyView.
This work clarifies how feedstocks and their structural features promote methanogenesis, and identifies the key regulatory factors, reducing pollution to the global environment, and also helps to alleviate the energy crisis. This is the first study to systematically link feedstock lignin content, pyrolysis conditions, biochar graphitization, and DIET ...
Caiyun Yang   +18 more
wiley   +1 more source

Leveraging pharmacy partnerships and Grant funding to improve access to medications for opioid use disorder. [PDF]

open access: yesExplor Res Clin Soc Pharm
Vasko JM   +6 more
europepmc   +1 more source

Carbon Catalyst Supports for Pt‐Based Polymer Electrolyte Membrane Fuel Cells: Porosity, Graphitization, and Chemical Modifications

open access: yesAdvanced Science, EarlyView.
This review explores recent advancements in understanding the influence of carbon support properties on the cathode performance of proton exchange membrane fuel cells. It proposes a set of properties deemed critical for the development of next‐generation carbon supports for the oxygen reduction reaction in fuel cells.
Camille Roiron   +5 more
wiley   +1 more source

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