Results 281 to 290 of about 1,894,591 (342)
Advanced Science, EarlyView.Brain metastases (BM) from lung cancer are aggressive with poor prognosis. This review covers clinical features, diagnosis, early metastasis, and multi‐omics‐elucidated mechanisms, especially the tumor microenvironment of lung cancer with BM. It also discusses preclinical models, signaling pathways, and emerging therapies.
Yixiang Zhu +5 more
wiley +1 more source
Advanced Science, EarlyView.Tracheoesophageal fistula (TEF), a pathological trachea‐esophagus connection, arises congenitally or from malignancy/radiotherapy/trauma, causing aspiration and malnutrition. Diagnosis utilizes imaging and endoscopy. Treatment ranges from endoscopic stenting to surgical repair and conservative management.
Gang Li +10 more
wiley +1 more source
Advanced Science, EarlyView.This study revealed that adiponectin facilitates the therapeutic efficiency of thrombopoietic agents by stimulating the membrane trafficking of c‐Mpl in MKs, which provides a point for ITP therapy. Moreover, a novel c‐Mpl trafficking mechanism based on the Myosin‐9/Rab6A complex is constructed. These findings provide new insights into the applicability
Xin Zhao +8 more
wiley +1 more source
Level of job satisfaction and its associated factors among midwives working in public health institutions, Northwest Ethiopia: a multi-center study. [PDF]
BMC Res NotesTibebu NS +7 more
europepmc +1 more source
Advanced Science, EarlyView.Researchers have identified a citrus chimera with distinctive tissue origins and carotenoid profiles. It is discovered that fruit tissues develop from all three cell layers but in different proportions. A key transcription factor, MYB107, regulates β‐cryptoxanthin production by directly activating carotenoid biosynthesis genes, explaining why some ...
Chi Zhang +8 more
wiley +1 more source
Drug Delivery Technologies for the Treatment of Age‐Related Macular Degeneration
Advanced Science, EarlyView.There are multiple therapeutic agents available for the treatment of both dry age‐related macular degeneration (AMD) and wet AMD. It is essential to continue innovation by introducing new drug delivery technologies that can incorporate those along with patient compliance and the accessibility of the technology into the early stages of research and ...
J Jesus Rodriguez‐Cruz +4 more
wiley +1 more source
The impacts of diagnosis-intervention packet payment on inpatient medical costs for hematologic malignancies and solid tumors: evidence from a retrospective study in China. [PDF]
Front Public HealthXu H, She Q, Zhang B, Zhang S, Xie L.
europepmc +1 more source
Advanced Science, EarlyView.ASP aggravates TEC injury and phenotypic transformation via mitochondrial dynamics disorder mediated by excessive Drp1 SUMOylation in DKD mice. However, either ASP deficiency or AASP effectively alleviates the kidney injury and mitochondrial dynamics disorder induced by STZ/HFD, highlighting that ASP could be an early diagnostic marker and potential ...
Qianqian Huang +8 more
wiley +1 more source
Incentive mechanism of foundation model enabled cross-silo federated learning. [PDF]
Sci RepZhang N, Xu X, Liu X, Wu J, Tang H.
europepmc +1 more source
Stacking Interventions Enhances Carbon Removals and Profitability of Livestock Production Systems
Advanced Science, EarlyView.The study indicates that stacking multiple interventions aimed at maximising soil organic carbon (SOC) sequestration and enteric methane (CH4) reductions realizes greater abatement and profit do any singular intervention, especially when SOC sequestration accounts for a significant proportion of greenhouse gas emissions (GHG) mitigation. Abstract While
My Pham‐Kieu +3 more
wiley +1 more source