Results 51 to 60 of about 2,233,596 (389)
This real‐world study of ROS1+ NSCLC highlights fusion diversity, treatment outcomes with crizotinib and lorlatinib, and in vitro experiments with resistance mechanisms. G2032R drives strong resistance to ROS1‐targeted TKIs, especially lorlatinib. Fusion partner location does not affect overall survival to crizotinib or lorlatinib. Findings support the
Fenneke Zwierenga +8 more
wiley +1 more source
The main objective of this thesis is to develop an architecture of the hybrid payment ...
Párhonyi, Róbert
core +2 more sources
Identifying prognostic targets in metastatic prostate cancer beyond AR
Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...
Emily Feng +13 more
wiley +1 more source
The authors propose to create a digital economy for the development of electric car charging networks for mass use in business, in fact, these are mechanisms of public-private partnerships.
Andrej V. Kochetkov +2 more
doaj +1 more source
The impact of mobile payment on payment choice
AbstractThis paper investigates the effect of mobile payment on the adoption and use of traditional payment instruments such as cash, checks, and credit, debit and prepaid cards at the point of sale (POS). Data are from a 2012 representative survey on consumer payment choice in the United States.
openaire +4 more sources
Payment instruments and collateral in the interbank payment system [PDF]
Abstract This paper presents a three-period model to analyze why banks need bank reserves despite the presence of other liquid assets, such as Treasury securities. The model shows that if a pair of banks settle bank transfers between them without the central bank, a hold-up problem occurs when they bargain over the terms of settlement.
openaire +4 more sources
Revising contract sum: the employer right to set-off payment [PDF]
Until today, dispute concerning payment had long plague the construction industry. Despite, on what was written on contract on agreed contract price, the employer always dissatisfied with contractor's work.
Saad, Hafiz
core
Ro 31‐8220 suppresses bladder cancer progression via enhancing autophagy in vitro and in vivo
The pan‐protein kinase C inhibitor Ro‐31‐8220 demonstrates potent anti‐bladder cancer effects both in vitro and in vivo by suppressing migration/invasion, inducing apoptosis and crucially activating autophagy, where blocking autophagy with chloroquine reduces its cell‐killing efficacy, suggesting its promise as a novel therapeutic candidate requiring ...
Shengjun Fu +12 more
wiley +1 more source
Soil liquefaction refers to the loss of strength and bearing capacity of soil under dynamic loads. Structures built on liquefied soils experience settlement.
Seyidcem Karakaş
doaj +1 more source
Production of antibacterial compounds by a Steely hybrid polyketide synthase in Dictyostelium
By selecting appropriate production species under optimised culture conditions, new chlorinated dibenzofuran compounds, which previously could not be analysed in sufficient quantities, were identified from cellular slime mould fruiting bodies. The strong antibacterial activity exhibited by these compounds suggests a link to the ecological function of ...
Tomoaki R. Yamashita +3 more
wiley +1 more source

