Results 201 to 210 of about 527,772 (339)

Sparse PCA corrects for cell type heterogeneity in epigenome-wide association studies

open access: yesNature Methods, 2016
Elior Rahmani   +10 more
semanticscholar   +1 more source

Acod1 Promotes PAD4 Ubiquitination via UBR5 Alkylation to Modulate NETosis and Exert Protective Effects in Sepsis

open access: yesAdvanced Science, EarlyView.
In this study, Acod1 knockout in CLP mice significantly increases peripheral blood NET levels, exacerbating inflammation, organ damage, and reducing survival. Further research shows that UBR5 interacts with PAD4, a key NET formation protein. Acod1/itaconate (ITA) enhances the enzymatic activity of UBR5 by alkylating the Cys2768 site, promoting the K48 ...
Huifan Liu   +10 more
wiley   +1 more source

Increased GPR35 expression is correlated with poor prognosis in prostate cancer. [PDF]

open access: yesWorld J Surg Oncol
Zhang T   +13 more
europepmc   +1 more source

Alnustone Ameliorates Metabolic Dysfunction‐Associated Steatotic Liver Disease by Facilitating Mitochondrial Fatty Acid β‐Oxidation via Targeting Calmodulin

open access: yesAdvanced Science, EarlyView.
This study identifies alnustone, a natural compound from Alpinia katsumadai, as a potent therapeutic agent for MASLD and MASH. Alnustone enhances mitochondrial fatty acid β‐oxidation by directly targeting calmodulin, improving liver steatosis, fibrosis, and insulin resistance in vivo.
Shourui Hu   +13 more
wiley   +1 more source

Identification of protein-coding genes associated with metastatic prostate cancer. [PDF]

open access: yesEndocr Relat Cancer
Sattari M   +7 more
europepmc   +1 more source

Radiographic Evaluation of PCA-type Total Knee Arthroplasty for Osteoarthritis of the Knee.

open access: bronze, 1995
Hirofumi Nakayama   +4 more
openalex   +2 more sources

Graph PCA Hashing for Similarity Search

open access: yesIEEE transactions on multimedia, 2017
Xiaofeng Zhu   +5 more
semanticscholar   +1 more source

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