Results 201 to 210 of about 1,131,696 (312)

Alkyltriphenylphosphonium Binding to Cardiolipin Triggers Oncosis in Cancer Cells

Advanced Science, EarlyView.
Alkyltriphenylphosphonium, exemplified by TPP+‐C14, preferentially accumulates in mitochondria and selectively binds to cardiolipin, a key phospholipid of the inner mitochondrial membrane, causing loss of mitochondrial membrane potential, severe cellular ATP depletion, and calcium imbalance.
Jin Li, Hang Zheng, Yuxing Lin, Ziwei Zhao, Yijia Mai, Zhangrong Lou, Qiang Liu, Zhao Ma, Chengjun Wu   +8 more
wiley   +1 more source

Bibliometric Insights into Aging and Immune Function in Prostate Cancer: Focus on Chronic Inflammation. [PDF]

J Inflamm Res
Lai S, Lin C, Li L, Qiu W, Zhang J, Guo T.   +5 more
europepmc   +1 more source

p16Ink4a‐Positive Hepatocytes Drive Liver Fibrosis Through Activation of LIFR Family Pathway

Advanced Science, EarlyView.
This study found that, following the long‐term CCl4 treatment, p16high hepatocytes appeared in zone 3, spatially co‐localizing with fibrotic areas. A specific cluster of p16high hepatocytes upregulated CTF1/LIF expression which induced HSC activation and further liver fibrosis, as revealed by single cell transcriptomic analysis.
Koji Nishikawa, Teh‐Wei Wang, Satoshi Kawakami, Shota Tanimoto, Kiyoshi Yamaguchi, Taketomo Kido, Masamichi Kimura, Tsunekazu Hishima, Yuki T. Okamura, Satotaka Omori, Takumi Iritani, Toshikaze Chiba, Takehiro Jimbo, Michio Katano, Kansuporn Kamataki, Ryoichi Yokoyama, Eigo Shimizu, Kiminori Kimura, Satoshi Yamzaki, Seiya Imoto, Yoichi Furukawa, Atsushi Miyajima, Yoshikazu Johmura, Makoto Nakanishi   +23 more
wiley   +1 more source

Obesity-linked genes may promote prostate cancer among Asian and Hispanic immigrants to North America. [PDF]

Front Public Health
Mercola D.
europepmc   +1 more source

A Mussel‐Inspired Bioadhesive Patch to Selectively Kill Glioblastoma Cells

Advanced Science, EarlyView.
An innovative mussel‐inspired bioadhesive patch has been developed for post‐surgical glioblastoma treatment. The patch, which adheres strongly in biological environments, releases a localized treatment. This treatment, acting via reactive oxygen species, shows specific toxicity to glioblastoma cells.
Jose Bolaños‐Cardet, Sara Pugliese, Jordi Bruna, Daniel Ruiz‐Molina, Salvio Suárez‐García, Victor J. Yuste   +5 more
wiley   +1 more source

The dual roles of exosomes in prostate cancer: mechanisms in tumorigenesis and avenues for clinical translation. [PDF]

Front Immunol
Yu M, Zhou D, Wei H, Wu T, Fan J, Ran G, Zhang C.   +6 more
europepmc   +1 more source

Hybrid Compression of Hyperspectral Images Based on PCA With Pre-Encoding Discriminant Information

IEEE Geoscience and Remote Sensing Letters, 2015
Chulhee Lee, S. Youn, T. Jeong, Eunjae Lee, J. Serra-Sagristà   +4 more
semanticscholar   +1 more source

Gαi1/3 Is a Novel Regulatory Target for RANKL Signal Transduction and Osteoporosis

Advanced Science, EarlyView.
ABSTRACT Osteoporosis, characterized by progressive bone loss and increased fracture risk, is a growing concern as the population ages. Current treatments, though advanced, remain limited, underscoring the necessity for novel therapeutic targets. Recent studies have shown that the immune system plays a key role in osteoporosis, with osteoclasts driving
Chaowen Bai, Mingchao Zhang, Le Liu, Lide Tao, Chenyang Xu, Hao Chai, Xin Shi, Yin Wang, Xiaopei Zhang, Qiong Chen, Dong Liu, Jinyu Bai, Chang She, Xiaozhong Zhou, Cong Cao, Huajian Shan   +15 more
wiley   +1 more source

Combination of serum TBL1XR1, MFAP5, and PSA as diagnostic biomarkers for prostate cancer. [PDF]

Clinics (Sao Paulo)
Wu X, Lin X, Lin J.
europepmc   +1 more source

Sparse PCA corrects for cell type heterogeneity in epigenome-wide association studies

Nature Methods, 2016
Elior Rahmani, N. Zaitlen, Yael Baran, C. Eng, D. Hu, J. Galanter, Sam S. Oh, E. Burchard, E. Eskin, J. Zou, E. Halperin   +10 more
semanticscholar   +1 more source