Results 201 to 210 of about 331,090 (323)

Leveraging Automated Machine Learning for Environmental Data‐Driven Genetic Analysis and Genomic Prediction in Maize Hybrids

open access: yesAdvanced Science, EarlyView.
An automated machine learning framework integrating environmental and genomic data enhances genetic analysis and genomic prediction in maize. By leveraging dimension‐reduced environmental parameters, it reveals trait‐environment relationships and identifies genetic markers that govern phenotypic plasticity and genotype‐by‐environment interactions.
Kunhui He   +12 more
wiley   +1 more source

YC‐4‐3, a Novel Glycogen Synthase Kinase 3β Inhibitor, Alleviates the Endoplasmic Reticulum Stress of Macrophages in Primary Immune Thrombocytopenia

open access: yesAdvanced Science, EarlyView.
A patented GSK‐3β inhibitor (GSK‐3βi), new benzothiazepinone compounds (BTZs), YC‐4‐3, can modulate the inflammatory status of macrophages in primary immune thrombocytopenia (ITP), and improve the thrombocytopenia in murine ITP models by directly interacting with endoplasmic reticulum (ER) stress response.
Pengcheng Xu   +10 more
wiley   +1 more source

Subsurface Oxygen Vacancy Mediated Surface Reconstruction and Depolarization of Ferroelectric BaTiO3 (001) Surface

open access: yesAdvanced Science, EarlyView.
In‐situ atomic‐scale electron microscopy reveals that vacuum‐annealed ferroelectric BaTiO3 (001) surfaces exhibit BaO termination with periodic Ba deficiency and TiOx adunits. Planar oxygen vacancy accumulation in the subsurface TiO2 layer mitigates the depolarization field, facilitating cooperative rumpling of surface and subsurface layers in a tail ...
Jeehun Jeong   +5 more
wiley   +1 more source

MicroRNA-18b-5p Inhibits the Malignant Progression of Prostate Cancer Through Downregulating TRAF5. [PDF]

open access: yesInt J Gen Med
Wang X   +9 more
europepmc   +1 more source

Radiographic Evaluation of PCA-type Total Knee Arthroplasty for Osteoarthritis of the Knee.

open access: bronze, 1995
Hirofumi Nakayama   +4 more
openalex   +2 more sources

Inhibition of the cyclin D1/E2F pathway by PCA‐4230, a potent repressor of cellular proliferation [PDF]

open access: green, 2001
David A. Goukassian   +5 more
openalex   +1 more source

Gut Microbiota Colonization in Early Life Influences Susceptibility to Adulthood Hepatic Lipid Accumulation in High‐Fat‐Diet‐Fed Mice

open access: yesAdvanced Science, EarlyView.
This study indicates that perinatal antibiotic exposure elevates susceptibility to high‐fat‐diet‐induced hepatic lipid accumulation via disrupting early‐life gut microbiota colonization. The decreased Lactobacillus colonization inhibits primary‐to‐secondary bile acid conversion, lowering secondary bile acids, enhancing adulthood intestinal lipid ...
Yan‐Yan Zhu   +11 more
wiley   +1 more source

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