Results 231 to 240 of about 919,275 (319)

Targeting YAP1-CD70 axis potentiates the efficacy of anti-PD-1 therapy in prostate cancer. [PDF]

Biomark Res
Tong T, Guan Y, Luo J, Yan B, Yang X, Zhang J, Yang Z, Cao F, Sun G, Zeng H, Li P, Pang J.   +11 more
europepmc   +1 more source

Gut Microbiota‐Derived Anandamide Mediates the Therapeutic Effects of Urolithin A on Alcohol‐Induced Cognitive and Social Dysfunction via CB1R‐DRD2‐RAP1 Signaling Axis

Advanced Science, EarlyView.
This study reveals that Urolithin A (UA) counteracts alcohol‐induced cognitive and social dysfunction (AICSD) via a gut microbiome‐dependent mechanism. UA‐enriched Bacteroids sartorii and Parabacteroids distasonis elevate anandamide (AEA), which activates the CB1R‐DRD2‐Rap1 signaling cascade to drive synaptic repair and reduce neuroinflammation ...
Hongbo Zhang, Zibin Li, Yao Xiao, Ji Bian, Caian He, Chao Liu, Lan Gong, Lin Han, Zhigang Liu, Min Wang   +9 more
wiley   +1 more source

Cuproptosis-related gene PROK1 predicts the diagnosis and prognosis of prostate cancer based on multiple machine learning. [PDF]

J Cancer
Qin X, Wang Q, Jiang W, Zhao Y, Li H, Zi T, Zhu Y, Li X, Xu C, Yang T, Wang X, Yao Y, Chen X, Zhou J, Wu G.   +14 more
europepmc   +1 more source

PCA and Eigenportfolio Construction : A Value-Information Approach 

Soham Mudalgikar, Andrew Papanicolaou
openalex   +1 more source

Gut Bacteria Improve Depressive Symptoms by Degrading Cortisol into Androgen

Advanced Science, EarlyView.
Chronic stress is an important risk factor for stress‐related disorders such as depression. Stress hormone cortisol is essential for the pathogenesis of stress‐related disorders such as depression. Some gut microbiota degraded cortisol, and improve depressive symptoms.
Xiong Wang, Qing Wu, Hao‐Long Zeng, Yin Shen, Hong‐Han Zhang, Jun Gong, Qi Zhang, Jia‐Zhao Xie, Da‐Wei Ye, Zi‐Yong Sun, Zhong‐Chun Liu, Li‐Ming Cheng, Di Li   +12 more
wiley   +1 more source

Machine-Learning-Based Prediction of Biochemical Recurrence in Prostate Cancer Integrating Fatty-Acid Metabolism and Stemness. [PDF]

Int J Mol Sci
Dai Z, Wang N, Liu M, Wang Z, Wei G.
europepmc   +1 more source

**Sequential Activation and Corridor Regimes in Two-Channel Systems: A PCA Diagnostic Analysis (with reproducible Python simulations)`

Elias De Jesus
openalex   +1 more source

Cancer Cell‐Intrinsic Cholesterol Induces Lipid‐Associated Macrophage Differentiation via SP1 Palmitoylation to Promote Prostate Cancer Progression

Advanced Science, EarlyView.
Cancer cell‐intrinsic cholesterol promotes the S‐palmitoylation of SP1, increasing its nuclear translocation and driving the transcription and secretion of MDK, which in turn facilitates the differentiation of macrophages into a lipid‐associated phenotype.
Shirong Peng, Weilong Lin, Zean Li, Ruilin Zhuang, Shengmeng Peng, Bingheng Li, Bingliang Chen, Yong Luo, Yuan Ou, Wei Zhuang, Tao Du, Kaiwen Li, Hai Huang   +12 more
wiley   +1 more source

APOBEC3C Suppresses Prostate Cancer by Regulating Key Molecules Involved in Cellular Inflammation, Cell Cycle Arrest, and DNA Damage Response. [PDF]

Cancers (Basel)
Pang Z, Wang J, Xu Y, Ji B, Ren M, Ding B.   +5 more
europepmc   +1 more source

Tensor robust PCA with nonconvex and nonlocal regularization

Xiaoyu Geng, Qiang Guo, Shuaixiong Hui, Ming Yang, Caiming Zhang   +4 more
openalex   +1 more source