Results 271 to 280 of about 919,275 (319)

FAM111B promotes prostate cancer progression by inhibiting apoptosis via ATF3 suppression and MAPK pathway activation: a novel biomarker and therapeutic target. [PDF]

Cancer Cell Int
Wang Y, Wang Z, Yin Z, Song T, He Y, Li M, Wang Z, Li Z, Wang P, Hu Z, Wang Z, Yu W, Cheng F.   +12 more
europepmc   +1 more source

Improving Lung Cancer Prediction with SMOTE, LASSO, and PCA: A Data-Driven Machine Learning Framework

Md. Jehadul Islam Mony, Md. Jalal Uddin Chowdhury   +1 more
openalex   +1 more source

HRS Degradation‐Induced Nicotinamide Deficiency in Placental Extracellular Vesicles Triggers Preeclampsia by Disrupting Maternal‐Fetal Immune Homeostasis

Advanced Science, EarlyView.
This study shows that lower NAM levels in PE‐derived pEVs correlate with disease severity. NAM‐deficient pEVs reduce Th1 and Th17 inhibition, leading to PE‐like symptoms. NAM in pEVs inhibits Th1 via SIRT1 and Th17 via macrophages. Reduced NAM in PE‐EVs is due to decreased HRS expression in trophoblasts, resulting from elevated HSP27.
Haiyi Fei, Yuhan Lin, Xiu Liu, Xiaohong Zhu, Xiaowen Lu, Zhan Shi, Fan Jia, Shiqian Xu, Ling Fang, Lingling Jiang, Songying Zhang   +10 more
wiley   +1 more source

Multi-Omics Analyses Reveal the Antifungal Mechanism of Phenazine-1-Carboxylic Acid Against Pseudogymnoascus destructans. [PDF]

J Fungi (Basel)
Huang Z, Sun S, Jin Z, Ji Y, Lu J, Xu T, Sun K, Li Z, Feng J.   +8 more
europepmc   +1 more source

Knowledge, Attitudes and Practices Among Anesthesia and Thoracic Surgery Medical Staff Toward Ai-PCA

Zhenghuan Song, Jiaqin Cai, Yihu Zhou, Yueyi Jiang, Shiyi Huang, Lianbing Gu, Jing Tan   +6 more
openalex   +2 more sources

Alkyltriphenylphosphonium Binding to Cardiolipin Triggers Oncosis in Cancer Cells

Advanced Science, EarlyView.
Alkyltriphenylphosphonium, exemplified by TPP+‐C14, preferentially accumulates in mitochondria and selectively binds to cardiolipin, a key phospholipid of the inner mitochondrial membrane, causing loss of mitochondrial membrane potential, severe cellular ATP depletion, and calcium imbalance.
Jin Li, Hang Zheng, Yuxing Lin, Ziwei Zhao, Yijia Mai, Zhangrong Lou, Qiang Liu, Zhao Ma, Chengjun Wu   +8 more
wiley   +1 more source

Protocatechuic acid attenuated inflammation caused by <i>Prevotella copri</i> and its metabolites. [PDF]

Virulence
Gong J, Ma S, Xiang H, Yang X, Zhang W, Hu R, Liu M, Fan Z, He J, Wu S.   +9 more
europepmc   +1 more source

Single‐Nucleus Multi‐Omics Reveals Hypoxia‐Driven Angiogenic Programs and Their Epigenetic Control in Sinonasal Squamous Cell Carcinoma

Advanced Science, EarlyView.
Single‐nucleus multi‐omics profiling of sinonasal squamous cell carcinoma unveils a hypoxia‐driven angiogenic axis. A specific hypoxic tumor subpopulation orchestrates endothelial tip cell differentiation via epigenetically regulated ADM and VEGFA secretion.
Chaelin You, Jaewoo Park, Jung Yeon Jang, Junho Noh, Jaehyun Lee, Geunho Kwon, Myeong Sang Yu, Yoo‐Sam Chung, Seung‐Jun Lee, Keunsoo Kang, Jihwan Park, Ji Heui Kim, Kyuho Kang   +12 more
wiley   +1 more source

Plant recognition by Trichoderma Harzianum elicits upregulation of a novel secondary metabolite cluster required for colonization. [PDF]

Sci Rep
Schalamun M, Li G, Hinterdobler W, Großkinsky DK, Compant S, Dreux-Zigha A, Gerke J, Cox R, Schmoll M.   +8 more
europepmc   +1 more source